Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-ZNFN1A2/HELIOS/IKZF2 Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

Zinc finger protein Helios is a protein that in humans is encoded by the IKZF2 gene. This gene is mapped to 2q34.This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.

Synonyms

Zinc finger protein Helios; Ikaros family zinc finger protein 2; IKZF2; HELIOS, ZNFN1A2

Gene Name

IKZF2

Gene ID

22807

UniProt

Q9UKS7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human ZNFN1A2/HELIOS/IKZF2 recombinant protein (Position: M1-R477) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. High expression in liver, spleen, pancreas and kidney.

Applications

Flow Cytometry

Field of Research

Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

Associates with Ikaros at centromeric heterochromatin.

References & Citations

1. Chessum, L., Matern, M. S., Kelly, M. C., Johnson, S. L., Ogawa, Y., Milon, B., McMurray, M., Driver, E. C., Parker, A., Song, Y., Codner, G., Esapa, C. T., and 11 others. Helios is a key transcriptional regulator of outer hair cell maturation. Nature 563: 696-700, 2018. 2. Gross, M. B. Personal Communication. Baltimore, Md. 2/15/2012. 3. Hosokawa, Y., Maeda, Y., Seto, M. Human Helios, an Ikaros-related zinc finger DNA binding protein: cDNA cloning and tissue expression pattern. Immunogenetics 50: 106-108, 1999.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

39411 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

IKAROS family zinc finger 2

Subcellular Location

Nucleus.

Protein Name

Zinc finger protein Helios

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

More Discoveries

Explore Other Products

Browse additional items from our catalog

Mouse Monoclonal XPF Antibody (OTI3H7) [DyLight 350]
NBP2-74882UV 0.1 mL

Mouse Monoclonal XPF Antibody (OTI3H7) [DyLight 350]

Sign In for Pricing
View Details
TNNC2, CT (TNNC2, Troponin C, skeletal muscle)
043105 200 µL

TNNC2, CT (TNNC2, Troponin C, skeletal muscle)

Sign In for Pricing
View Details
hsa-miR-6837-3p miRNA Inhibitor
MIH03635 2x 5.0 nmol

hsa-miR-6837-3p miRNA Inhibitor

Sign In for Pricing
View Details
CHIR-98014 50mg
A11085-50 50 mg

CHIR-98014 50mg

Sign In for Pricing
View Details
PF-06700841 (Brepocitinib) free base 10mg
A17176-10 10 mg

PF-06700841 (Brepocitinib) free base 10mg

Sign In for Pricing
View Details
Human ZNF229 Pre-designed siRNA Set A
SI018692A 1 Each

Human ZNF229 Pre-designed siRNA Set A

Sign In for Pricing
View Details