Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-MORC3 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

MORC family CW-type zinc finger protein 3 is a protein that in humans is encoded by the MORC3 gene. This gene is mapped to 21q22.12. This gene encodes a protein that localizes to the nuclear matrix and forms nuclear bodies via an ATP-dependent mechanism. The protein is predicted to have coiled-coil and zinc finger domains and has RNA binding activity. Alternative splicing produces multiple transcript variants encoding distinct isoforms.

Synonyms

MORC family CW-type zinc finger protein 3; Nuclear matrix protein 2; Zinc finger CW-type coiled-coil domain protein 3; MORC3; KIAA0136; NXP2; ZCWCC3

Gene Name

MORC3

Gene ID

23515

UniProt

Q14149

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human MORC3, identical to the related mouse and rat sequences.

Clonality

Polyclonal

Tissue Specificity

Expressed in heart, placenta, skeletal muscle, brain, pancreas, lung, liver, but not kidney.

Applications

Flow Cytometry

Field of Research

Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism. Sumoylated MORC3-NBs can also associate with PML-NBs. Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity. Binds RNA in vitro. May be required for influenza A transcription during viral infection.

References & Citations

1. Kimura, Y., Sakai, F., Nakano, O., Kisaki, O., Sugimoto, H., Sawamura, T., Sadano, H., Osumi, T. The newly identified human nuclear protein NXP-2 possesses three distinct domains, the nuclear matrix-binding, RNA-binding, and coiled-coil domains. J. Biol. Chem. 277: 20611-20617, 2002. 2. Nagase, T., Seki, N., Tanaka, A., Ishikawa, K., Nomura, N. Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. DNA Res. 2: 167-174, 1995.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

80420 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

MORC family CW-type zinc finger 3

Subcellular Location

Nucleoplasm. Nucleus matrix. PML body.

Protein Name

MORC family CW-type zinc finger protein 3

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

UGT2B10 (UDP-glucuronosyltransferase 2B10, UDPGT 2B10, UDPGT2B10) (MaxLight 490)
MBS6203995-01 0.1 mL

UGT2B10 (UDP-glucuronosyltransferase 2B10, UDPGT 2B10, UDPGT2B10) (MaxLight 490)

Ask
View Details
UGT2B10 (UDP-glucuronosyltransferase 2B10, UDPGT 2B10, UDPGT2B10) (MaxLight 490)
MBS6203995-02 5x 0.1 mL

UGT2B10 (UDP-glucuronosyltransferase 2B10, UDPGT 2B10, UDPGT2B10) (MaxLight 490)

Ask
View Details
TMS1 (PYCARD) Human qPCR Template Standard (NM_145183)
HK211783 1 Kit

TMS1 (PYCARD) Human qPCR Template Standard (NM_145183)

Ask
View Details
Human PLA2G2E/Group IIE secretory phospholipase A2 ELISA Kit
MBS2906553-01 48 Well

Human PLA2G2E/Group IIE secretory phospholipase A2 ELISA Kit

Ask
View Details
Human PLA2G2E/Group IIE secretory phospholipase A2 ELISA Kit
MBS2906553-02 96 Well

Human PLA2G2E/Group IIE secretory phospholipase A2 ELISA Kit

Ask
View Details
Human PLA2G2E/Group IIE secretory phospholipase A2 ELISA Kit
MBS2906553-03 5x 96 Well

Human PLA2G2E/Group IIE secretory phospholipase A2 ELISA Kit

Ask
View Details