Anti-RTL10 Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
RTL10 (Retrotransposon Gag Like 10) is a Protein Coding gene. This gene is mapped to 22q11.21. It could induce apoptosis in a BH3 domain-dependent manner. The interaction network of Bcl-2 family members may play a key role in modulation RTL10/BOP intrinsic apoptotic signaling activity. Diseases associated with RTL10 include Hemophagocytic Lymphohistiocytosis, Familial, 3.
Synonyms
Protein Bop; BH3-only protein; Retrotransposon Gag-like protein 10; RTL10; BOP, C22orf29
Gene Name
RTL10
Gene ID
79680
UniProt
Q7L3V2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human RTL10.
Clonality
Polyclonal
Tissue Specificity
Ubiquitously expressed.
Applications
Flow Cytometry
Field of Research
Chemokines, Immunology, Innate Immunity
Purification
Immunogen affinity purified.
Form
Liquid
Function
Could induce apoptosis in a BH3 domain-dependent manner. The interaction network of Bcl-2 family members may play a key role in modulation RTL10/BOP intrinsic apoptotic signaling activity.
References & Citations
1. Zhang X, Weng C, Li Y, Wang X, Jiang C, Li X, Xu Y, Chen Q, Pan L, Tang H. Human Bop is a novel BH3-only member of the Bcl-2 protein family. Protein Cell. 2012 Oct;3 (10) :790-801. doi: 10.1007/s13238-012-2069-7. Epub 2012 Oct 11.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
14377 MW
Specificity
No cross reactivity with other proteins.
Applications Notes
6
Gene Name Synonym
Retrotransposon Gag like 10
Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Protein Name
Lymphocyte antigen 6A-2/6E-1
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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