Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-CD5 Antibody Picoband® (monoclonal, 4E2) Fluoro647 Conjugated

Product Specifications

Background

CD5 is a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. In humans, the gene is located on the long arm of chromosome 11. This protein is a type-I transmembrane glycoprotein found on the surface of thymocytes, T lymphocytes and a subset of B lymphocytes. The encoded protein contains three SRCR domains and may act as a receptor to regulate T-cell proliferation. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms

T-cell surface glycoprotein CD5; Lymphocyte antigen T1/Leu-1; CD5; CD5; LEU1

Gene Name

CD5

Gene ID

921

UniProt

P06127

Host

Mouse

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived human CD5 recombinant protein (Position: R25-L495) .

Clonality

Monoclonal

Clone

Clone: 4E2

Tissue Specificity

Brain, liver, placenta, lymphocytes and erythrocytes.

Applications

Flow Cytometry

Field of Research

Cell Adhesion, Cell Type Markers, Cytoskeleton/ECM, Hematopoietic Progenitors, Immunology, Integrins, Myeloid, Signal Transduction, Stem Cells

Purification

Immunogen affinity purified.

Form

Liquid

Function

May act as a receptor in regulating T-cell proliferation.

References & Citations

1. Lundell, A.-C., Johansen, S., Adlerberth, I., Wold, A. E., Hesselmar, B., Rudin, A. High proportion of CD5+ B cells in infants predicts development of allergic disease. J. Immun. 193: 510-518, 2014. 2. Zhang, C., Xin, H., Zhang, W., Yazaki, P. J., Zhang, Z., Le, K., Li, W., Lee, H., Kwak, L., Forman, S., Jove, R., Yu, H. CD5 binds to interleukin-6 and induces a feed-forward loop with the transcription factor STAT3 in B cells to promote cancer. Immunity 44: 913-923, 2016.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M00480-2-Fluoro647

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

CD5 molecule

Subcellular Location

Cell membrane; Single-pass type I membrane protein

Protein Name

Integrin beta-2

Isotype

Mouse IgG1

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Pyrex Test Tubes 150 x 24mm with rim 1.2mm medium wall
TES2018 100 / PCK

Pyrex Test Tubes 150 x 24mm with rim 1.2mm medium wall

Ask
View Details
O10J5 Polyclonal Antibody
UB-GEN-7418 100 ul

O10J5 Polyclonal Antibody

Ask
View Details
Rat Homocysteic Acid, Hcy Elisa Kit
EKC39198 96 Tests

Rat Homocysteic Acid, Hcy Elisa Kit

Ask
View Details
Nibrin (Nijmegen Breakage Syndrome, NBS1) (AP)
MBS6241851-01 0.1 mL

Nibrin (Nijmegen Breakage Syndrome, NBS1) (AP)

Ask
View Details
Nibrin (Nijmegen Breakage Syndrome, NBS1) (AP)
MBS6241851-02 5x 0.1 mL

Nibrin (Nijmegen Breakage Syndrome, NBS1) (AP)

Ask
View Details
Isofebrifugin
AB1101 20 mg

Isofebrifugin

Ask
View Details