What sizes are available for Anti-IFNAR2 Antibody Picoband® Fluoro647 Conjugated?

Anti-IFNAR2 Antibody Picoband® Fluoro647 Conjugated is available in the following size(s): 100 µg/Vial.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Anti-IFNAR2 Antibody Picoband® Fluoro647 Conjugated

Q: What is the catalog number for Anti-IFNAR2 Antibody Picoband® Fluoro647 Conjugated?

The catalog number for Anti-IFNAR2 Antibody Picoband® Fluoro647 Conjugated is A02056-3-Fluoro647.

Q: Is Anti-IFNAR2 Antibody Picoband® Fluoro647 Conjugated in stock?

Anti-IFNAR2 Antibody Picoband® Fluoro647 Conjugated is currently made to order / not held in immediate stock. Contact us for lead time.

Selected Variant

A02056-3-Fluoro647

Size: 100 µg/Vial

Product Specifications

Background

Interferon-alpha/beta receptor beta chain is a protein that in humans is encoded by the IFNAR2 gene. It is mapped to 21q22.11. The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene.

Synonyms

Interferon alpha/beta receptor 2; IFN-R-2; IFN-alpha binding protein; IFN-alpha/beta receptor 2; Interferon alpha binding protein; Type I interferon receptor 2; IFNAR2; IFNABR; IFNARB

Gene Name

IFNAR2

Gene ID

3455

UniProt

P48551

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human IFNAR2 recombinant protein (Position: D33-Q466) .

Clonality

Polyclonal

Tissue Specificity

Isoform 3 is detected in the urine. Expressed in blood cells. Expressed in lymphoblastoid and fibrosarcoma cell lines.

Applications

Flow Cytometry

Field of Research

Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are ly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 is a potent inhibitor of type I IFN receptor activity.

References & Citations

1. Croze, E., Russell-Harde, D., Wagner, T. C., Pu, H., Pfeffer, L. M., Perez, H. D. The human type I interferon receptor: identification of the interferon beta-specific receptor-associated phosphoprotein. J. Biol. Chem. 271: 33165-33168, 1996. 2. Croze, E., Usacheva, A., Asarnow, D., Minshall, R.D., Perez, H.D., Colamonici, O. Receptor for activated C-kinase (RACK-1), a WD motif-containing protein, specifically associates with the human type I IFN receptor. J. Immun. 165: 5127-5132, 2000.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

37492 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

Gene Name Synonym

Interferon alpha and beta receptor subunit 2

Subcellular Location

Cell membrane. Single-pass type I membrane protein. Secreted.

Protein Name

G2/mitotic-specific cyclin-B2

Isotype

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Price

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

BNUB0963-500 1x 500 µL