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Anti-Loricrin/LOR Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

Loricrin is a protein that in humans is encoded by the LOR gene. It is mapped to 1q21.3. Loricrin is a major protein component of the cornified cell envelope found in terminally differentiatedepidermal cells. It is expressed in the granular layer of all keratinized epithelial cells of mammals tested including oral, esophageal and stomach mucosa of rodents, tracheal squamous metaplasia of vitamin A deficient hamster and estrogen induced squamous vaginal epithelium of rats.

Synonyms

Loricrin; LOR; LRN

Gene Name

LOR

Gene ID

4014

UniProt

P23490

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Loricrin/LOR recombinant protein (Position: M1-K312) .

Clonality

Polyclonal

Tissue Specificity

Expressed in testis and to a lesser degree in brain, ovary and placenta. Found in most tissues at low levels.

Applications

Flow Cytometry

Field of Research

Cell Biology, Cytokines, Epigenetics and Nuclear Signaling, Immunology, Innate Immunity, Interferons, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ubiquitin & Ubiquitin Like Modifiers, Ubiquitin E3 Enzymes

Purification

Immunogen affinity purified.

Form

Liquid

Function

Major keratinocyte cell envelope protein.

References & Citations

1. Hohl D, Mehrel T, Lichti U, Turner ML, Roop DR, Steinert PM (May 1991) . Characterization of human loricrin. Structure and function of a new class of epidermal cell envelope proteins. J Biol Chem. 266 (10) : 6626–36. 2. Yoneda K, Hohl D, McBride OW, Wang M, Cehrs KU, Idler WW, Steinert PM (Oct 1992) . The human loricrin gene. J Biol Chem. 267 (25) : 18060–6.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A05290-1-Fluoro647

Calculated Molecular Weight

39411 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Loricrin

Subcellular Location

Nucleoplasm. Cytoplasm.

Protein Name

Zinc finger protein Helios

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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