Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-TRPC5 Antibody Picoband® Fluoro594 Conjugated

Product Specifications

Background

Short transient receptor potential channel 5 (TrpC5) also known as transient receptor protein 5 (TRP-5) is a protein that in humans is encoded by the TRPC5 gene. It is mapped to Xq23. This gene belongs to the transient receptor family. It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins. The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. The protein is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. It also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na (+) -H+ exchange regulatory factor (NHERF), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1) .

Synonyms

Short transient receptor potential channel 5; TrpC5; Transient receptor protein 5; TRP-5; hTRP-5; hTRP5; TRPC5; TRP5

Gene Name

TRPC5

Gene ID

7224

UniProt

Q9UL62

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human TRPC5 recombinant protein (Position: L378-L973) .

Clonality

Polyclonal

Tissue Specificity

Expressed in brain with higher levels in fetal brain. Found in cerebellum and occipital pole.

Applications

Flow Cytometry

Field of Research

Calcium Channels, Calcium Signaling, Metabolism, Neuroscience, Neurotransmission, Plasma Membrane, Signal Transduction, Signaling Pathway

Purification

Immunogen affinity purified.

Form

Liquid

Function

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective. May also be activated by intracellular calcium store depletion.

References & Citations

1. Entrez Gene: transient receptor potential cation channel. 2. Greka, A., Navarro, B., Oancea, E., Duggan, A., Clapham, D. E. TRPC5 is a regulator of hippocampal neurite length and growth cone morphology. Nature Neurosci. 6: 837-845, 2003. 3. Sossey-Alaoui, K., Lyon, J. A., Jones, L., Abidi, F. E., Hartung, A. J., Hane, B., Schwartz, C. E., Stevenson, R. E., Srivastava, A. K. Molecular cloning and characterization of TRPC5 (HTRP5), the human homologue of a mouse brain receptor-activated capacitative Ca (2+) entry channel. Genomics 60: 330-340, 1999.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

91791 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Transient receptor potential cation channel subfamily C member 5

Subcellular Location

Cell membrane. Multi-pass membrane protein.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Iobitridol
MF-0044516 25 mg

Iobitridol

Ask
View Details
Rabbit Anti-Rat Protein Kinase C Gamma (PKCg) Polyclonal Antibody
VD1N465 1 Each

Rabbit Anti-Rat Protein Kinase C Gamma (PKCg) Polyclonal Antibody

Ask
View Details
Anti-STELLAR antibody
STJ70882 100 µg

Anti-STELLAR antibody

Ask
View Details
PROCR Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI5A8]
TA805662BM 100 µL

PROCR Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI5A8]

Ask
View Details
Mettl7a2 (NM_199477) Mouse Tagged ORF Clone Lentiviral Particle
MR203037L4V 200 µL

Mettl7a2 (NM_199477) Mouse Tagged ORF Clone Lentiviral Particle

Ask
View Details