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Anti-GLUT6/SLC2A6 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Solute carrier family 2, facilitated glucose transporter member 6 is a protein that in humans is encoded by the SLC2A6 gene. It is mapped to 9q34.2. Hexose transport into mammalian cells is catalyzed by a family of membrane proteins, including SLC2A6, that contain 12 transmembrane domains and a number of critical conserved residues.

Synonyms

Solute carrier family 2, facilitated glucose transporter member 6; Glucose transporter type 6; GLUT-6; Glucose transporter type 9; GLUT-9; SLC2A6; GLUT9

Gene Name

SLC2A6

Gene ID

11182

UniProt

Q9UGQ3

Host

Rabbit

Reactivity

Human, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human GLUT6/SLC2A6 recombinant protein (Position: M1-R507) .

Clonality

Polyclonal

Tissue Specificity

Highly expressed in brain, spleen and peripheral blood leukocytes.

Applications

Flow Cytometry

Field of Research

Cancer, Channels, Metabolism, Plasma Membrane, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

Facilitative glucose transporter; binds cytochalasin B with low affinity.

References & Citations

1. Doege, H., Bocianski, A., Joost, H.-G., Schurmann, A. Activity and genomic organization of human glucose transporter 9 (GLUT9), a novel member of the family of sugar-transport facilitators predominantly expressed in brain and leucocytes. Biochem. J. 350: 771-776, 2000. Note: Erratum: Biochem. J. 358: 791-792, 2001. 2. Fan, Y.-S., Eddy, R. L., Byers, M. G., Haley, L. L., Henry, W. M., Kayano, T., Shows, T. B., Bell, G. I. Assignment of genes encoding three human glucose transporter/transporter-like proteins (GLUT4, GLUT5 and GLUT6) to chromosomes 17, 1 and 5, respectively. (Abstract) Cytogenet. Cell Genet. 51: 997 only, 1989. 3. Gould, G. W., Holman, G. D. The glucose transporter family: structure, function and tissue-specific expression. Biochem. J. 295: 329-341, 1993.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Solute carrier family 2 member 6

Subcellular Location

Cell membrane. Multi-pass membrane protein.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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