Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-CCDC36 Antibody Picoband®

Boster Bio Anti-CCDC36 Antibody Picoband® catalog # A14775. Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

CCDC36, also known as CT74 (cancer/testis antigen 74), is a 584 amino acid protein that contains coiled-coil domains and is expressed as three alternatively spliced isoforms. The gene encoding CCDC36 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Synonyms

Interactor of HORMAD1 protein 1; Cancer/testis antigen 74; CT74; Coiled-coil domain-containing protein 36; CCDC36; IHO1

Gene Name

CCDC36

Gene ID

339834

UniProt

Q8IYA8

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human CCDC36 recombinant protein (Position: E172-N472) .

Clonality

Polyclonal

Tissue Specificity

Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Applications

ELISA, IF, IHC, ICC, WB

Field of Research

Cell Biology

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.

References & Citations

1. Stanzione M., Baumann M., Papanikos F., Dereli I., Lange J., Ramlal A., Traenkner D., Shibuya H., de Massy B., Watanabe Y., Jasin M., Keeney S., Toth A. Meiotic DNA break formation requires the unsynapsed chromosome axis-binding protein IHO1 (CCDC36) in mice. Nat. Cell Biol. 18:1208-1220 (2016)

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

64099 MW

Observed Molecular Weight

66 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Coiled-coil domain containing 36

Subcellular Location

Chromosome.

Protein Name

DAP3 binding cell death enhancer 1

Isotype

Rabbit IgG

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Rabbit anti-Schizosaccharomyces pombe (strain 972/24843)(Fission yeast) SPAP27G11.02 Polyclonal Antibody
MBS9008653 Inquire

Rabbit anti-Schizosaccharomyces pombe (strain 972/24843)(Fission yeast) SPAP27G11.02 Polyclonal Antibody

Ask
View Details
JHDM2b, CT (KDM3B, C5orf7, JHDM2B, JMJD1B, KIAA1082, Lysine-specific demethylase 3B, JmjC domain-containing histone demethylation protein 2B, Jumonji domain-containing protein 1B, Nuclear protein 5qNCA)
037193 200 µL

JHDM2b, CT (KDM3B, C5orf7, JHDM2B, JMJD1B, KIAA1082, Lysine-specific demethylase 3B, JmjC domain-containing histone demethylation protein 2B, Jumonji domain-containing protein 1B, Nuclear protein 5qNCA)

Ask
View Details
D830030K20Rik (NM_177135) Mouse Tagged Lenti ORF Clone
MR224399L4 10 µg

D830030K20Rik (NM_177135) Mouse Tagged Lenti ORF Clone

Ask
View Details
OPA1 (Dynamin-like 120kD Protein, Mitochondrial, Optic Atrophy Protein 1, KIAA0567) APC
MBS6388031-01 0.1 mL

OPA1 (Dynamin-like 120kD Protein, Mitochondrial, Optic Atrophy Protein 1, KIAA0567) APC

Ask
View Details
OPA1 (Dynamin-like 120kD Protein, Mitochondrial, Optic Atrophy Protein 1, KIAA0567) APC
MBS6388031-02 5x 0.1 mL

OPA1 (Dynamin-like 120kD Protein, Mitochondrial, Optic Atrophy Protein 1, KIAA0567) APC

Ask
View Details
2,4,7-Trichlorofluorene
420402-01 50 mg

2,4,7-Trichlorofluorene

Ask
View Details