Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-HECTD3 Antibody Picoband®

Boster Bio Anti-HECTD3 Antibody Picoband® catalog # A11560. Tested in Flow Cytometry, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

The protein encoded by this gene transfers ubiquitin from an E2 ubiquitin-conjugating enzyme to targeted substrates, leading to the degradation of those substrates. This gene is mapped to 1p34.1. The encoded protein has been shown to transfer ubiquitin to TRIOBP to facilitate cell cycle progression, and to STX8.

Synonyms

E3 ubiquitin-protein ligase HECTD3; HECT domain-containing protein 3; HECT-type E3 ubiquitin transferase HECTD3; HECTD3

Gene Name

HECTD3

Gene ID

79654

UniProt

Q5T447

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human HECTD3, identical to the related mouse and rat sequences.

Clonality

Polyclonal

Tissue Specificity

Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.

Applications

Flow Cytometry, IHC, IHC-F, ICC, WB

Field of Research

Cell Biology, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ubiquitin E3 Enzymes

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then ly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus faciliting cell cycle progression by regulating the turn-over of TRIOBP. Mediates also ubiquitination of STX8.

References & Citations

1. Yu J., Lan J., Zhu Y., Li X., Lai X., Xue Y., Jin C., Huang H. The E3 ubiquitin ligase HECTD3 regulates ubiquitination and degradation of Tara. Biochem. Biophys. Res. Commun. 367:805-812 (2008)

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

97 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

HECT domain E3 ubiquitin protein ligase 3

Subcellular Location

Perinuclear region.

Isotype

Rabbit IgG

Contents

243

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Rabbit Polyclonal PDZD11 Antibody [Janelia Fluor 585]
NBP3-21435JF585 0.1 mL

Rabbit Polyclonal PDZD11 Antibody [Janelia Fluor 585]

Ask
View Details
ZNF133 Antibody, HRP conjugated
A38721-100UG 100 µg

ZNF133 Antibody, HRP conjugated

Ask
View Details
Osteopontin (OPN), Recombinant, Human, His-Tag, GST-Tag
057246-01 10 µg

Osteopontin (OPN), Recombinant, Human, His-Tag, GST-Tag

Ask
View Details
Osteopontin (OPN), Recombinant, Human, His-Tag, GST-Tag
057246-02 50 µg

Osteopontin (OPN), Recombinant, Human, His-Tag, GST-Tag

Ask
View Details
Osteopontin (OPN), Recombinant, Human, His-Tag, GST-Tag
057246-03 100 µg

Osteopontin (OPN), Recombinant, Human, His-Tag, GST-Tag

Ask
View Details
Osteopontin (OPN), Recombinant, Human, His-Tag, GST-Tag
057246-04 200 µg

Osteopontin (OPN), Recombinant, Human, His-Tag, GST-Tag

Ask
View Details