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Anti-Peptide YY/PYY Antibody Fluoro647 Conjugated

Product Specifications

Background

Take control of your experiments with tailored peptides. Our custom peptide synthesis allows you to take full control of your research objectives. Partner with us to access an extensive range of modifications and optimize your peptide properties for ultimate success. custom peptide synthesis

Synonyms

Peptide YY; PYY; PYY-I; Peptide tyrosine tyrosine; Peptide YY (3-36) ; PYY-II

Gene Name

PYY

Gene ID

5697

UniProt

P10082

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human Peptide YY/PYY, which shares 91.7% amino acid (aa) sequence identity with both mouse and rat Peptide YY/PYY.

Clonality

Polyclonal

Tissue Specificity

Isoform 1, isoform 3 and isoform 5 are ubiquitous. Isoform 2 is strongly expressed in the brain, weakly detectable in lung and colon, and overexpressed in gastric cancer. Isoform 4 is not detected in normal tissues, but strong expression was found in gastric cancer tissues. Down-regulated in a subset of cases of breast cancer. .

Applications

Flow Cytometry

Field of Research

Cell Biology, Cell Cycle, Cell Differentiation, Epigenetics and Nuclear Signaling

Purification

Immunogen affinity purified.

Form

Liquid

Function

This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.

References & Citations

1. Liu C, Aloia T, Adrian T, Newton T, Bilchik A, Zinner M, Ashley S, McFadden D (1996) . Peptide YY: a potential proabsorptive hormone for the treatment of malabsorptive disorders. Am Surg 62 (3) : 232–6. 2. Taylor IL (March 1985) . Distribution and release of peptide YY in dog measured by specific radioimmunoassay. Gastroenterology 88 (3) : 731–7.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

87794 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Peptide YY

Subcellular Location

Secreted.

Protein Name

Transforming acidic coiled-coil-containing protein 1

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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