Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-ACTN3 Antibody Picoband® (monoclonal, 9B5) Fluoro594 Conjugated

Product Specifications

Background

Alpha-actinin-3, also known as alpha-actinin skeletal muscle isoform 3 or F-actin cross-linking protein, is a protein that in humans is encoded by the ACTN3 gene. This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the coding allele. The non-functional allele of this gene is associated with elite athlete status.

Synonyms

Alpha-actinin-3; Alpha-actinin skeletal muscle isoform 3; F-actin cross-linking protein; ACTN3

Gene Name

ACTN3

Gene ID

89

UniProt

Q08043

Host

Mouse

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human ACTN3, different from the related mouse sequence by five amino acids.

Clonality

Monoclonal

Clone

Clone: 9B5

Tissue Specificity

Expressed only in a subset of type 2 skeletal muscle fibers.

Applications

Flow Cytometry

Field of Research

Actin Binding Proteins, Actin, etc., Cytoskeleton, Cytoskeleton/ECM, Microfilaments, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.

References & Citations

1. Papadimitriou ID, Papadopoulos C, Kouvatsi A, Triantaphyllidis C (April 2008) . The ACTN3 gene in elite Greek track and field athletes. Int J Sports Med 29 (4) : 352–5. 2. Yang N, MacArthur DG, Gulbin JP, Hahn AG, Beggs AH, Easteal S, North K (September 2003) . ACTN3 genotype is associated with human elite athletic performance. Am. J. Hum. Genet. 73 (3) : 627–31.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Actinin alpha 3 (gene/pseudogene)

Isotype

Mouse IgG1

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

More Discoveries

Explore Other Products

Browse additional items from our catalog

TNFSF12 Protein Vector (Human) (pPB-C-His)
PV059153 500 ng

TNFSF12 Protein Vector (Human) (pPB-C-His)

Sign In for Pricing
View Details
Human SYCP1 Knockout HEK293T cell line
GTR15422596 1 Vial

Human SYCP1 Knockout HEK293T cell line

Sign In for Pricing
View Details
RGD1308114 3'UTR Luciferase Stable Cell Line
TU217751 1.0 mL

RGD1308114 3'UTR Luciferase Stable Cell Line

Sign In for Pricing
View Details
Guinea pig Myosin light Chain (MLC) ELISA Kit
NSL0482Gp 96 Tests

Guinea pig Myosin light Chain (MLC) ELISA Kit

Sign In for Pricing
View Details
Human SOWAHB siRNA
abx934703-01 15 nmol

Human SOWAHB siRNA

Sign In for Pricing
View Details
Human SOWAHB siRNA
abx934703-02 30 nmol

Human SOWAHB siRNA

Sign In for Pricing
View Details