Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-FCGR2A Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Low affinity immunoglobulin gamma Fc region receptor II-a is a protein that in humans is encoded by the FCGR2A gene. This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. It is mapped to 1q23.3. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.

Synonyms

Low affinity immunoglobulin gamma Fc region receptor II-a; IgG Fc receptor II-a; CDw32; Fc-gamma RII-a; Fc-gamma-RIIa; FcRII-a; CD32; FCGR2A; CD32; FCG2; FCGR2A1; IGFR2

Gene Name

FCGR2A

Gene ID

2212

UniProt

P12318

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived human FCGR2A recombinant protein (Position: Q34-M210) .

Clonality

Polyclonal

Tissue Specificity

Found on monocytes, neutrophils and eosinophil platelets.

Applications

Flow Cytometry

Field of Research

Hematopoietic Progenitors, Immunoglobulins, Immunology, Lymphoid, Myeloid, Receptors, Stem Cells, T Lymphocytic Lineage

Purification

Immunogen affinity purified.

Form

Liquid

Function

Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.

References & Citations

1. Asano, K., Matsushita, T., Umeno, J., Hosono, N., Takahashi, A., Kawaguchi, T., Matsumoto, T., Matsui, T., Kakuta, Y., Kinouchi, Y., Shimosegawa, T., Hosokawa, M., Arimura, Y., Shinomura, Y., Kiyohara, Y., Tsunoda, T., Kamatani, N., Iida, M., Nakamura, Y., Kubo, M. A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population. Nature Genet. 41: 1325-1329, 2009. 2. De Rose, V., Arduino, C., Cappello, N., Piana, R., Salmin, P., Bardessono, M., Goia, M., Padoan, R., Bignamini, E., Costantini, D., Pizzamiglio, G., Bennato, V., Colombo, C., Giunta, A., Piazza, A. Fc-gamma receptor IIA genotype and susceptibility to P. aeruginosa infection in patients with cystic fibrosis.Europ. J. Hum. Genet. 13: 96-101, 2005.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

51561 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Fc fragment of IgG receptor IIa

Subcellular Location

Cell membrane.

Protein Name

Keratin, type I cytoskeletal 14

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

More Discoveries

Explore Other Products

Browse additional items from our catalog

Hematopoietic Cell Freezing Medium
041-50 50 mL

Hematopoietic Cell Freezing Medium

Sign In for Pricing
View Details
Granulocyte-Macrophage Colony-Stimulating Factor (CSF2) Antibody
abx130918-01 100 µL

Granulocyte-Macrophage Colony-Stimulating Factor (CSF2) Antibody

Sign In for Pricing
View Details
Granulocyte-Macrophage Colony-Stimulating Factor (CSF2) Antibody
abx130918-02 200 µL

Granulocyte-Macrophage Colony-Stimulating Factor (CSF2) Antibody

Sign In for Pricing
View Details
Granulocyte-Macrophage Colony-Stimulating Factor (CSF2) Antibody
abx130918-03 1 mL

Granulocyte-Macrophage Colony-Stimulating Factor (CSF2) Antibody

Sign In for Pricing
View Details
PI3K-IN-19 (hydrochloride)
HY-141690A 1 Each

PI3K-IN-19 (hydrochloride)

Sign In for Pricing
View Details
Biological Microscope BMIC-501
BMIC-501 1 Unit

Biological Microscope BMIC-501

Sign In for Pricing
View Details