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Anti-Smoothelin/SMTN Antibody Picoband®

Boster Bio Anti-Smoothelin/SMTN Antibody Picoband® catalog # A04895. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Smoothelin is a protein that in humans is encoded by the SMTN gene. This gene encodes a structural protein that is found exclusively in contractile smooth muscle cells. It associates with stress fibers and constitutes part of the cytoskeleton. This gene is localized to chromosome 22q12.3, distal to the TUPLE1 locus and outside the DiGeorge syndrome deletion. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Synonyms

Smoothelin; SMTN; SMSMO

Gene Name

SMTN

Gene ID

6525

UniProt

P53814

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human Smoothelin, which shares 97.3% amino acid (aa) sequence identity with mouse Smoothelin.

Clonality

Polyclonal

Tissue Specificity

Smooth muscle; contractile or vascular (for the long form) .

Applications

WB

Field of Research

Vasculature

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Structural protein of the cytoskeleton.

References & Citations

1. Engelen JJ, Esterling LE, Albrechts JC, Detera-Wadleigh SD, van Eys GJ (Sep 1997) . Assignment of the human gene for smoothelin (SMTN) to chromosome 22q12 by fluorescence in situ hybridization and radiation hybrid mapping. Genomics. 43 (2) : 245–7. 2. van der Loop FT, Schaart G, Timmer ED, Ramaekers FC, van Eys GJ (Sep 1996) . Smoothelin, a novel cytoskeletal protein specific for smooth muscle cells. J Cell Biol. 134 (2) : 401–11.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

56903 MW

Observed Molecular Weight

120 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Smoothelin

Subcellular Location

Cytoplasm, cytoskeleton. Exhibits a filamentous organization.

Protein Name

Vesicular acetylcholine transporter

Isotype

Rabbit IgG

Contents

243

Frequently Asked Questions

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