Anti-JunD Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
Transcription factor JunD is a protein that in humans is encoded by the JUND gene. The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation initiation site usage results in the production of different isoforms.
Synonyms
Transcription factor jun-D; JUND
Gene Name
JUND
Gene ID
3727
UniProt
P17535
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human JunD, identical to the related mouse and rat sequences.
Clonality
Polyclonal
Applications
Flow Cytometry
Field of Research
Cancer, Cancer Susceptibility, Cardiovascular, Domain Families, Epigenetics and Nuclear Signaling, Hlh/Leucine Zipper, Hypertrophy, Immunology, Innate Immunity, Oncoproteins, Oncoproteins/Suppressors, Proto-Oncogenes, TLR Signaling, Transcription, Transcription Factors
Purification
Immunogen affinity purified.
Form
Liquid
Function
Transcription factor binding AP-1 sites.
References & Citations
1. Entrez Gene: JUND jun D proto-oncogene. 2. Berger I, Shaul Y (June 1991) . Structure and function of human jun-D. Oncogene. 6 (4) : 561–6. 3. Nomura N, Ide M, Sasamoto S, Matsui M, Date T, Ishizaki R (July 1990) . Isolation of human cDNA clones of jun-related genes, jun-B and jun-D. Nucleic Acids Res. 18 (10) : 3047–8.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
35,174 MW
Specificity
No cross reactivity with other proteins.
Applications Notes
6
Gene Name Synonym
JunD proto-oncogene, AP-1 transcription factor subunit
Subcellular Location
Nucleus.
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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