Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-HDAC10 Antibody Picoband® Fluoro647 Conjugated

Selected Variant

A05215-2-Fluoro647

Size: 100 µg/Vial

Product Specifications

Background

Histone deacetylase 10 is an enzyme that in humans is encoded by the HDAC10 gene. The protein encoded by this gene belongs to the histone deacetylase family, members of which deacetylate lysine residues on the N-terminal part of the core histones. Histone deacetylation modulates chromatin structure, and plays an important role in transcriptional regulation, cell cycle progression, and developmental events. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms

Histone deacetylase 10; HD10; HDAC10

Gene Name

HDAC10

Gene ID

83933

UniProt

Q969S8

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived human HDAC10 recombinant protein (Position: T3-Q290) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. High expression in liver, spleen, pancreas and kidney.

Applications

Flow Cytometry

Field of Research

Acetylation, Chromatin Modifying Enzymes, Class I, Epigenetics and Nuclear Signaling, Signaling Pathways, Stem Cells

Purification

Immunogen affinity purified.

Form

Liquid

Function

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.

References & Citations

1. Entrez Gene: HDAC10 histone deacetylase 10. 2. Kao HY, Lee CH, Komarov A, Han CC, Evans RM (Jan 2002) . Isolation and characterization of mammalian HDAC10, a novel histone deacetylase. J Biol Chem. 277 (1) : 187–93. 3. Guardiola AR, Yao TP (Jan 2002) . Molecular cloning and characterization of a novel histone deacetylase HDAC10. J Biol Chem. 277 (5) : 3350–6.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

39411 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Histone deacetylase 10

Subcellular Location

Cytoplasm. Nucleus. Excluded from the nucleoli.

Protein Name

Long-chain-fatty-acid--CoA ligase 5

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Price

Sign In for Pricing

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Anti-KBTBD2 Antibody Picoband®, Carrier-free
A15277-1-carrier-free 100 µg/Vial

Anti-KBTBD2 Antibody Picoband®, Carrier-free

Sign In for Pricing
View Details
Anti-UGGT/UGT1/UGGT1 Antibody Picoband®, Dylight550 Conjugate
A10212-2-Dylight550 100 µg

Anti-UGGT/UGT1/UGGT1 Antibody Picoband®, Dylight550 Conjugate

Sign In for Pricing
View Details
CD79a (IGA/515), 0.2mg/mL
BNUB0515-100 1x 100 µL

CD79a (IGA/515), 0.2mg/mL

Sign In for Pricing
View Details
Anti-RGS9 Antibody Picoband® (Biotine Conjugate)
PA2241-Biotin 100 µg/Vial

Anti-RGS9 Antibody Picoband® (Biotine Conjugate)

Sign In for Pricing
View Details
Cytokeratin 20 (KRT20) (Colorectal Epithelial Marker) (KRT20/1993), CF740 conjugate, 0.1mg/mL
BNC741993-100 1x 100 µL

Cytokeratin 20 (KRT20) (Colorectal Epithelial Marker) (KRT20/1993), CF740 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
CD5 (Mantle Cell Lymphoma Marker) (CD5/2416), CF488A conjugate, 0.1mg/mL
BNC882416-100 1x 100 µL

CD5 (Mantle Cell Lymphoma Marker) (CD5/2416), CF488A conjugate, 0.1mg/mL

Sign In for Pricing
View Details