Anti-NFIB/NF1B2 Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Synonyms
Nuclear factor 1 B-type; NF1-B; Nuclear factor 1/B; CCAAT-box-binding transcription factor; CTF; Nuclear factor I/B; NF-I/B; NFI-B; TGGCA-binding protein; NFIB
Gene Name
NFIB
Gene ID
4781
UniProt
O00712
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human NFIB/NF1B2, identical to the related mouse and rat sequences.
Clonality
Polyclonal
Applications
Flow Cytometry
Field of Research
Epigenetics and Nuclear Signaling, Neurogenesis, Neurology Process, Neuroscience, Transcription
Purification
Immunogen affinity purified.
Form
Liquid
Function
Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
References & Citations
1. Gründer, Albert; Ebel, Thorsten T.; Mallo, Moisés; Schwarzkopf, Georg; Shimizu, Takehiko; Sippel, Albrecht E.; Schrewe, Heinrich (2002-03-01) . Nuclear factor I-B (Nfib) deficient mice have severe lung hypoplasia. Mechanisms of Development. 112 (1–2) : 69–77. 2. Steele-Perkins, George; Plachez, Céline; Butz, Kenneth G.; Yang, Guanhu; Bachurski, Cindy J.; Kinsman, Stephen L.; Litwack, E. David; Richards, Linda J.; Gronostajski, Richard M. (2005-01-15) . The Transcription Factor Gene Nfib Is Essential for both Lung Maturation and Brain Development. Molecular and Cellular Biology. 25 (2) : 685–698.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Specificity
No cross reactivity with other proteins.
Applications Notes
6
Gene Name Synonym
Nuclear factor I B
Subcellular Location
Nucleus.
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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