Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-CLPP Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

ATP-dependent Clp protease proteolytic subunit (ClpP) is an enzyme that in humans is encoded by the CLPP gene. It is mapped to 19p13.3. The protein encoded by this gene belongs to the peptidase family S14 and hydrolyzes proteins into small peptides in the presence of ATP and magnesium. The protein is transported into mitochondrial matrix and is associated with the inner mitochondrial membrane.

Synonyms

ATP-dependent Clp protease proteolytic subunit, mitochondrial; Endopeptidase Clp; CLPP

Gene Name

CLPP

Gene ID

8192

UniProt

Q16740

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived human CLPP recombinant protein (Position: A184-H247) .

Clonality

Polyclonal

Tissue Specificity

Detected in liver (at protein level) . Predominantly expressed in skeletal muscle. Intermediate levels in heart, liver and pancreas. Low in brain, placenta, lung and kidney.

Applications

Flow Cytometry

Field of Research

Cancer, Metabolism, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Pathways and Processes, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates.

References & Citations

1. Entrez Gene: CLPP ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli) . 2. Bross P, Andresen BS, Knudsen I, Kruse TA, Gregersen N (Feb 1996) . Human ClpP protease: cDNA sequence, tissue-specific expression and chromosomal assignment of the gene. FEBS Lett. 377 (2) : 249–52. 3. Corydon, TJ; Bross, P; Holst, HU; Neve, S; Kristiansen, K; Gregersen, N; Bolund, L (1 April 1998) . A human homologue of Escherichia coli ClpP caseinolytic protease: recombinant expression, intracellular processing and subcellular localization.. The Biochemical Journal. 331 (1) : 309–16.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A01117-1-Fluoro647

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Caseinolytic mitochondrial matrix peptidase proteolytic subunit

Subcellular Location

Mitochondrion matrix.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Dmkn (NM_028618) Mouse Tagged ORF Clone Lentiviral Particle
MR219388L3V 200 µL

Dmkn (NM_028618) Mouse Tagged ORF Clone Lentiviral Particle

Ask
View Details
Anti-CHRNA4 Antibody (N-Term)
M02230-200ul 200 µL

Anti-CHRNA4 Antibody (N-Term)

Ask
View Details
AIM1L Polyclonal Antibody, PE-Cy5 Conjugated
bs-9093R-PE-Cy5 100 µL

AIM1L Polyclonal Antibody, PE-Cy5 Conjugated

Ask
View Details
HEI10 Polyclonal Antibody
BT-AP03936-01 20 µL

HEI10 Polyclonal Antibody

Ask
View Details
HEI10 Polyclonal Antibody
BT-AP03936-02 50 µL

HEI10 Polyclonal Antibody

Ask
View Details
HEI10 Polyclonal Antibody
BT-AP03936-03 100 µL

HEI10 Polyclonal Antibody

Ask
View Details