Anti-TCP1 eta/CCT7 Antibody Picoband®

T-complex protein 1 subunit eta is a protein that in humans is encoded by the CCT7 gene. This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6.

T-complex protein 1 subunit eta; TCP-1-eta; CCT-eta; HIV-1 Nef-interacting protein; T-complex protein 1 subunit eta, N-terminally processed; CCT7; CCTH; NIP7-1

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity) . .

1. Entrez Gene: CCT7 chaperonin containing TCP1, subunit 7 (eta) . 2. Won KA, Schumacher RJ, Farr GW, Horwich AL, Reed SI (Dec 1998) . Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT. Molecular and Cellular Biology. 18 (12) : 7584–9.

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.