Anti-S100A10 Antibody Picoband® Fluoro647 Conjugated
Product Specifications
Background
S100 calcium-binding protein A10 (S100A10), also known as p11, is a protein that is encoded by the S100A10 gene in humans and the S100a10 gene in other species. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis.
Synonyms
Protein S100-A10; Calpactin I light chain; Calpactin-1 light chain; Cellular ligand of annexin II; S100 calcium-binding protein A10; p10 protein; p11; S100A10; ANX2LG; CAL1L; CLP11
Gene Name
S100A10
Gene ID
6281
UniProt
P60903
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E. coli-derived human S100A10 recombinant protein (Position: Q4-K94) .
Clonality
Polyclonal
Applications
Flow Cytometry
Field of Research
Signal Transduction, Signaling Pathway, Cytoskeleton/ECM, Calcium Binding Proteins, Calcium Signaling, Cell Adhesion
Purification
Immunogen affinity purified.
Form
Liquid
Function
Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine- specific kinase.
References & Citations
1. Entrez Gene: S100A10 S100 calcium binding protein A10. 2. O'Connell, P. A., Surette, A. P., Liwski, R. S., Svenningsson, P., Waisman, D. M. S100A10regulates plasminogen-dependent macrophage invasion. Blood 116: 1136-1146, 2010.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
12252 MW
Specificity
No cross reactivity with other proteins.
Applications Notes
6
Gene Name Synonym
S100 calcium binding protein A10
Subcellular Location
Alpha-beta T cell receptor complex; external side of plasma membrane; immunological synapse; cell body; cell-cell junction; dendritic spine; integral component of membrane
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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