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Anti-Uteroglobin/Scgb1a1 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Uteroglobin, also known as secretoglobin family 1A member 1 (SCGB1A1), is a protein that in humans is encoded by the SCGB1A1 gene. This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma.

Synonyms

Uteroglobin; Clara cell phospholipid-binding protein; CCPBP; Clara cells 10 kDa secretory protein; CC10; PCB-binding protein; Secretoglobin family 1A member 1; Scgb1a1; Cc10; Ugb; Utg

Gene Name

Scgb1a1

Gene ID

25575

UniProt

P17559

Host

Rabbit

Reactivity

Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived rat Uteroglobin recombinant protein (Position: S20-V96) .

Clonality

Polyclonal

Tissue Specificity

Clara cells (nonciliated cells of the surface epithelium of the pulmonary airways) .

Applications

Flow Cytometry

Field of Research

Immunoglobulins, Immunology

Purification

Immunogen affinity purified.

Form

Liquid

Function

Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.

References & Citations

1. Klug J, Beier HM, Bernard A, Chilton BS, Fleming TP, Lehrer RI, Miele L, Pattabiraman N, Singh G (2000) . Uteroglobin/Clara cell 10-kDa family of proteins: nomenclature committee report. Ann. N. Y. Acad. Sci. 923: 348–54. 2. Stripp B R, Reynolds S D, Boe I, Lund J, Power J H T, Coppens, J T, Wong V, Reynolds P R, Plopper C G (2002) . Clara Cell Secretory Protein Deficiency Alters Clara Cell Secretory Apparatus and the Protein Composition of Airway Lining Fluid. Am. J. Respir. Cell Mol. Biol. 27 (2) : 170–8.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

31568 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Secretoglobin family 1A member 1

Subcellular Location

Secreted.

Protein Name

Aquaporin-3

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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