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Anti-Uteroglobin/Scgb1a1 Antibody Picoband®

Boster Bio Anti-Uteroglobin/Scgb1a1 Antibody Picoband® catalog # A02201-2. Tested in ELISA, IHC, WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Uteroglobin, also known as secretoglobin family 1A member 1 (SCGB1A1), is a protein that in humans is encoded by the SCGB1A1 gene. This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma.

Synonyms

Uteroglobin; Clara cell phospholipid-binding protein; CCPBP; Clara cells 10 kDa secretory protein; CC10; PCB-binding protein; Secretoglobin family 1A member 1; Scgb1a1; Cc10; Ugb; Utg

Gene Name

Scgb1a1

Gene ID

25575

UniProt

P17559

Host

Rabbit

Reactivity

Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived rat Uteroglobin recombinant protein (Position: S20-V96) .

Clonality

Polyclonal

Tissue Specificity

Clara cells (nonciliated cells of the surface epithelium of the pulmonary airways) .

Applications

ELISA (Cap), IHC, WB

Field of Research

Immunoglobulins, Immunology

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.

References & Citations

1. Klug J, Beier HM, Bernard A, Chilton BS, Fleming TP, Lehrer RI, Miele L, Pattabiraman N, Singh G (2000) . Uteroglobin/Clara cell 10-kDa family of proteins: nomenclature committee report. Ann. N. Y. Acad. Sci. 923: 348–54. 2. Stripp B R, Reynolds S D, Boe I, Lund J, Power J H T, Coppens, J T, Wong V, Reynolds P R, Plopper C G (2002) . Clara Cell Secretory Protein Deficiency Alters Clara Cell Secretory Apparatus and the Protein Composition of Airway Lining Fluid. Am. J. Respir. Cell Mol. Biol. 27 (2) : 170–8.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

31568 MW

Observed Molecular Weight

10 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Secretoglobin family 1A member 1

Subcellular Location

Secreted.

Protein Name

Aquaporin-3

Isotype

Rabbit IgG

Contents

243

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