Anti-GRO alpha/Cxcl1 Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets.
Synonyms
Growth-regulated alpha protein; C-X-C motif chemokine 1; Cytokine-induced neutrophil chemoattractant 1; CINC-1; Platelet-derived growth factor-inducible protein KC; Cxcl1; Cinc1; Gro; Scyb1
Gene Name
Cxcl1
Gene ID
81503
UniProt
P14095
Host
Rabbit
Reactivity
Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E. coli-derived rat GRO alpha recombinant protein (Position: A25-K96) .
Clonality
Polyclonal
Tissue Specificity
At least expressed in the lung and trachea.
Applications
Flow Cytometry
Field of Research
Cytokines, G Protein Signaling, Immunology, Innate Immunity, Signal Transduction, Signaling Pathway
Purification
Immunogen affinity purified.
Form
Liquid
Function
Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation.
References & Citations
1. Anisowicz, A., Zajchowski, D., Stenman, G., Sager, R. Functional diversity of GRO gene expression in human fibroblasts and mammary epithelial cells. Proc. Nat. Acad. Sci. 85: 9645-9649, 1988. 2. Horuk, R., Yansura, D. G., Reilly, D., Spencer, S., Bourell, J., Henzel, W., Rice, G., Unemori, E. Purification, receptor binding analysis, and biological characterization of human melanoma growth stimulating activity (MGSA) : evidence for a novel MGSA receptor. J. Biol. Chem. 268: 541-546, 1993. 3. O'Donovan, N., Galvin, M., Morgan, J. G. Physical mapping of the CXC chemokine locus on human chromosome 4. Cytogenet. Cell Genet. 84: 39-42, 1999.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Specificity
No cross reactivity with other proteins.
Applications Notes
6
Gene Name Synonym
C-X-C motif chemokine ligand 1
Subcellular Location
Secreted.
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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