Anti-NAP2/Ppbp Antibody Picoband® Fluoro647 Conjugated

Chemokine (C-X-C motif) ligand 7 (CXCL7), also known as NAP2 or Pro-Platelet basic protein (PPBP), is a human gene. The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. Furthermore, the protein is an antimicrobial protein with bactericidal and antifungal activity.

Chemokine (C-X-C motif) ligand 7, isoform CRA_b ; Chemokine subfamily B Cys-X-Cys ; Platelet basic protein ; Pro-platelet basic protein ; Putative uncharacterized protein ; Thymus chemokine 1 ; Ppbp ; Cxcl7 ; mCG_1702

1. Entrez Gene: PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) . 2. Hristov M, Zernecke A, Bidzhekov K; et al. (March 2007) . Importance of CXC chemokine receptor 2 in the homing of human peripheral blood endothelial progenitor cells to sites of arterial injury.Circ. Res. 100 (4) : 590–7. 3. Majumdar S, Gonder D, Koutsis B, Poncz M (1991) . Characterization of the human beta-thromboglobulin gene. Comparison with the gene for platelet factor 4. J Biol Chem 266 (9) : 5785–9.