Anti-Epigen/EPGN Antibody Picoband® Fluoro594 Conjugated

Product Specifications

Background

Epigen, also known as epithelial mitogen, is a protein that in humans is encoded by the EPGN gene. The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate.

Synonyms

Epigen; Epithelial mitogen; EPG; EPGN; UNQ3072/PRO9904

Gene Name

EPGN

Gene ID

255324

UniProt

Q6UW88

Host

Rabbit

Reactivity

Human, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived human Epigen recombinant protein (Position: A23-K110) . Human Epigen shares 85.7% amino acid (aa) sequence identity with mouse Epigen.

Clonality

Polyclonal

Applications

Flow Cytometry

Field of Research

Cancer, Growth Factors, Growth Factors/Hormones, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases. .

References & Citations

1. Entrez Gene: Epithelial mitogen. 2. Schneider MR, Yarden Y (2014) . Structure and function of epigen, the last EGFR ligand. Semin. Cell Dev. Biol. 28: 57–61.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

17091 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

Gene Name Synonym

Epigen

Subcellular Location

Isoform 1: Membrane ; Single- pass type I membrane protein .

Isotype

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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Anti-Epigen/EPGN Antibody Picoband® Fluoro594 Conjugated

Product Specifications

Background

Synonyms

Gene Name

Gene ID

UniProt

Host

Reactivity

Cross Reactivity

Immunogen

Clonality

Applications

Field of Research

Purification

Form

Function

References & Citations

Storage Conditions

Calculated Molecular Weight

Specificity

Applications Notes

Gene Name Synonym

Subcellular Location

Isotype

Contents

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