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Anti-Epigen/EPGN Antibody Picoband®

Boster Bio Anti-Epigen/EPGN Antibody Picoband® catalog # A10011-1. Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Epigen, also known as epithelial mitogen, is a protein that in humans is encoded by the EPGN gene. The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate.

Synonyms

Epigen; Epithelial mitogen; EPG; EPGN; UNQ3072/PRO9904

Gene Name

EPGN

Gene ID

255324

UniProt

Q6UW88

Host

Rabbit

Reactivity

Human, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived human Epigen recombinant protein (Position: A23-K110) . Human Epigen shares 85.7% amino acid (aa) sequence identity with mouse Epigen.

Clonality

Polyclonal

Applications

WB

Field of Research

Cancer, Growth Factors, Growth Factors/Hormones, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases. .

References & Citations

1. Entrez Gene: Epithelial mitogen. 2. Schneider MR, Yarden Y (2014) . Structure and function of epigen, the last EGFR ligand. Semin. Cell Dev. Biol. 28: 57–61.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

17091 MW

Observed Molecular Weight

17 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Epigen

Subcellular Location

Isoform 1: Membrane ; Single- pass type I membrane protein .

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

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