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Anti-Sca1/Ly6A/E Antibody Picoband® Fluoro594 Conjugated

Product Specifications

Background

Stem cell antigen-1 (Sca-1) is a mouse glycosyl phosphatidylinositol-anchored protein and a cell surface marker found on hematopoietic stem cells (HSCs) . It is encoded by the strain-specific Ly-6 E/A allelic gene. Sca-1 has been discovered in several non hematopoietic tissues and can be used to enrich progenitor cell populations other than HSC. It is suggested that Sca-1 could be involved in regulating both B and T cell activation.

Synonyms

Lymphocyte antigen 6A-2/6E-1; Ly-6A.2/Ly-6E.1; Stem cell antigen 1; SCA-1; T-cell-activating protein; TAP; Ly6a; Ly6

Gene Name

Ly6a

Gene ID

110454

UniProt

P05533

Host

Rabbit

Reactivity

Mouse

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of mouse Sca1/Ly6A/E.

Clonality

Polyclonal

Tissue Specificity

Widely expressed. .

Applications

Flow Cytometry

Field of Research

Chemokines, Immunology, Innate Immunity

Purification

Immunogen affinity purified.

Form

Liquid

Function

T-cell activation.

References & Citations

1. Codias, E.K. et al. (1990) J. Immunol. 144:2197. 2. Malek, T.R. et al. (1986) J. Exp. Med. 164:709 .

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

14377 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Lymphocyte antigen 6A-2/6E-1

Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor.

Protein Name

Lymphocyte antigen 6A-2/6E-1

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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