What is the catalog number for Anti-TRPC3 Antibody Picoband®?

The catalog number for Anti-TRPC3 Antibody Picoband® is A01472.

What sizes are available for Anti-TRPC3 Antibody Picoband®?

Anti-TRPC3 Antibody Picoband® is available in the following size(s): 100 µg/Vial.

Is Anti-TRPC3 Antibody Picoband® in stock?

Anti-TRPC3 Antibody Picoband® is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-TRPC3 Antibody Picoband®?

The safety data sheet for Anti-TRPC3 Antibody Picoband® is available here: https://www.bosterbio.com/msds?sku=A01472.

Anti-TRPC3 Antibody Picoband®

Boster Bio Anti-TRPC3 Antibody Picoband® catalog # A01472. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Short transient receptor potential channel 3 (TrpC3) also known as transient receptor protein 3 (TRP-3) is a protein that in humans is encoded by the TRPC3 gene. The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms

Short transient receptor potential channel 3; TrpC3; Transient receptor protein 3; TRP-3; hTrp-3; hTrp3; TRPC3; TRP3

Gene Name

TRPC3

Gene ID

7222

UniProt

Q13507

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human TRPC3 recombinant protein (Position: R718-L770) . Human TRPC3 shares 96.2% amino acid (aa) sequence identity with both mouse and rat TRPC3.

Clonality

Polyclonal

Tissue Specificity

Expressed predominantly in brain and at much lower levels in ovary, colon, small intestine, lung, prostate, placenta and testis.

Applications

Field of Research

Calcium Channels, Calcium Signaling, Cardiovascular, Hypertrophy, Neurogenesis, Neurology Process, Neuroscience, Signal Transduction, Signaling Pathway, Vasculature

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol 1,4,5- triphosphate receptors (ITPR) with bound IP3. May also be activated by internal calcium store depletion. .

References & Citations

1. Fusco FR, Martorana A, Giampà C, De March Z, Vacca F, Tozzi A, Longone P, Piccirilli S, Paolucci S, Sancesario G, Mercuri NB, Bernardi G (July 2004) . Cellular localization of TRPC3 channel in rat brain: preferential distribution to oligodendrocytes. Neuroscience Letters. 365 (2) : 137–42. 2. Li HS, Xu XZ, Montell C (1999) . Activation of a TRPC3-dependent cation current through the neurotrophin BDNF. Neuron. 24 (1) : 261–73. 3. Zhou FW, Matta SG, Zhou FM (January 2008) . Constitutively active TRPC3 channels regulate basal ganglia output neurons. The Journal of Neuroscience. 28 (2) : 473–82.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

106 kDa

Observed Molecular Weight

106 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Short transient receptor potential channel 3

Subcellular Location

Membrane; Multi-pass membrane protein.

Protein Name

Short transient receptor potential channel 3

Isotype

Rabbit IgG

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Frequently Asked Questions

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Anti-TRPC3 Antibody Picoband®

Product Specifications

Background

Synonyms

Gene Name

Gene ID

UniProt

Host

Reactivity

Cross Reactivity

Immunogen

Clonality

Tissue Specificity

Applications

Field of Research

Purification

Concentration

Form

Reconstitution

Function

References & Citations

Storage Conditions

Calculated Molecular Weight

Observed Molecular Weight

Specificity

Gene Name Synonym

Subcellular Location

Protein Name

Isotype

Contents

Frequently Asked Questions

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