Anti-Amylase/AMY1A/AMY1B/AMY1C Antibody Picoband® Fluoro488 Conjugated
Selected Variant
A12967-Fluoro488
Size: 100 µg/Vial
Product Specifications
Background
Amylase is an enzyme that catalyses the breakdown of starch into sugars. Amylase is present in human saliva, where it begins the chemical process of digestion. By in situ hybridization combined with high resolution cytogenetics, the amylase gene is mapped to 1p21. Amylase enzymes find use in bread making and to break down complex sugars such as starch (found in flour) into simple sugars. Yeast then feeds on these simple sugars and converts it into the waste products of alcohol and CO2.
Synonyms
Alpha-amylase 1;3.2.1.1;1,4-alpha-D-glucan glucanohydrolase 1; Salivary alpha-amylase; AMY1A; AMY1; AMY1B; AMY1; AMY1C; AMY1
Gene Name
AMY1A
Gene ID
276/277/278
UniProt
P04745
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human Alpha Amylase 1, different from the related mouse sequence by five amino acids, and from the related rat sequence by six amino acids.
Clonality
Polyclonal
Tissue Specificity
Highly expressed in the kidney, brain and testis and to a lower extent in heart, liver and small intestine. Expressed in the lens, cornea and retina. Strongly expressed in the distal tips of the retinal neuroepithelium that form the iris and ciliary body.
Applications
Flow Cytometry
Field of Research
Complement, Immunology, Innate Immunity
Purification
Immunogen affinity purified.
Form
Liquid
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
References & Citations
1. Dracopoli, N. C., Meisler, M. H.Mapping the human amylase gene cluster on the proximal short arm of chromosome 1 using a highly informative (CA) n repeat.Genomics 7: 97-102, 1990. 2. Gumucio, D. L., Wiebauer, K., Caldwell, R. M., Samuelson, L. C., Meisler, M. H.Concerted evolution of human amylase genes.Molec. Cell. Biol. 8: 1197-1205, 1988. 3. Kamaryt, J., Laxova, R.Amylase heterogeneity: some genetic and clinical aspects.Humangenetik 1: 579-586, 1965.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
57768 MW
Specificity
No cross reactivity with other proteins.
Applications Notes
6
Gene Name Synonym
Alpha-amylase 1
Subcellular Location
Secreted.
Protein Name
Alpha-amylase 1
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Price
Sign In for Pricing
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
A05215-2-PE 100 µg/Vial
Anti-HDAC10 Antibody Picoband® (PE Conjugate)
Sign In for Pricing
View Details 
BNC742350-100 1x 100 µL
GPN1 / XAB1 (DNA Repair & Protein Synthesis) (GPN1/2350), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC742318-100 1x 100 µL
ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC741604-100 1x 100 µL
CD4 (T-Helper/Inducer Cell Marker) (CD4/1604), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
PA1621-PE 100 µg/Vial
Anti-Integrin alpha 3/ITGA3 Antibody Picoband®, PE Conjugate
Sign In for Pricing
View Details