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Anti-Hepatitis B Virus Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Hepatitis B virus, abbreviated HBV, is a species of the genus Orthohepadnavirus, which is likewise a part of the Hepadnaviridae family of viruses. This virus causes the disease hepatitis B. It consists of HBsAg, HBcAg (HBeAg is a splice variant), Hepatitis B virus DNA polymerase and HBx. Among these, HBsAg (also known as the Australia antigen) is the surface antigen of the hepatitis B virus (HBV) . It indicates current hepatitis B infection. The viral envelope of an enveloped virus has different surface proteins from the rest of the virus which act as antigens. These antigens are recognized by antibody proteins that bind specifically to one of these surface proteins.

Synonyms

Large S protein ; S

Gene Name

S

Gene ID

944569

UniProt

D2X4M3

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human Hepatitis B Virus.

Clonality

Polyclonal

Tissue Specificity

Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Applications

Flow Cytometry

Field of Research

Cell Biology, Cell Type Markers, Tags & Cell Markers

Purification

Immunogen affinity purified.

Form

Liquid

Function

Involved in cellular response to oxidative stress.

References & Citations

1. Magnius LO, Norder H (1995) . Subtypes, genotypes and molecular epidemiology of the hepatitis B virus as reflected by sequence variability of the S-gene. Intervirology. 38 (1–2) : 24–34. 2. Rysgaard, Carolyn D; Morris, Cory S; Drees, Denny; Bebber, Tami; Davis, Scott R; Kulhavy, Jeff; Krasowski, Matthew D (2012) . Positive hepatitis B surface antigen tests due to recent vaccination: a persistent problem. BMC Clinical Pathology. 12 (1) : 15. doi:10.1186/1472-6890-12-15. Retrieved11 March 2014.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

6374 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Long surface protein; PreS1; L protein; LHBs; large S protein; pre-S1/pre-S2/S regions; L glycoprotein; L-HBsAG; LHBs

Subcellular Location

Secreted.

Protein Name

Large S protein

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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