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Anti-ST7 Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

Suppressor of tumorigenicity protein 7 is a protein that in humans is encoded by the ST7 gene. The gene for this product maps to a region on chromosome 7 identified as an autism-susceptibility locus. Mutation screening of the entire coding region in autistic individuals failed to identify phenotype-specific variants, suggesting that coding mutations for this gene are unlikely to be involved in the etiology of autism. The function of this gene product has not been determined. Transcript variants encoding different isoforms of this protein have been described.?

Synonyms

Suppressor of tumorigenicity 7 protein; Protein FAM4A1; Protein HELG; ST7; FAM4A1, HELG, RAY1

Gene Name

ST7

Gene ID

7982

UniProt

Q9NRC1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human ST7, identical to the related mouse and rat sequences.

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed, with highest levels in heart, liver and pancreas. .

Applications

Flow Cytometry

Field of Research

Cancer, Oncoproteins/Suppressors, Tumor Suppressors

Purification

Immunogen affinity purified.

Form

Liquid

Function

May act as a tumor suppressor. .

References & Citations

1. Ogata T, Ayusawa D, Namba M, Takahashi E, Oshimura M, Oishi M (October 1993) . Chromosome 7 suppresses indefinite division of nontumorigenic immortalized human fibroblast cell lines KMST-6 and SUSM-1. Molecular and Cellular Biology. 13 (10) : 6036–43. 2. Zenklusen JC, Rodriguez LV, LaCava M, Wang Z, Goldstein LS, Conti CJ (November 1996) . Novel susceptibility locus for mouse hepatomas: evidence for a conserved tumor suppressor gene. Genome Research. 6 (11) : 1070–6.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

67166 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Suppressor of tumorigenicity 7 protein

Subcellular Location

Membrane ; Multi-pass membrane protein .

Protein Name

Suppressor of tumorigenicity 7 protein

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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