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Anti-TREX2 Antibody Picoband®

Boster Bio Anti-TREX2 Antibody Picoband® catalog # PB10105. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Three prime repair exonuclease 2 is an enzyme that in humans is encoded by the TREX2 gene. By genomic sequence analysis, the TREX2 gene is mapped to chromosome Xq28. This gene encodes a protein with 3' exonuclease activity. Enzymes with this activity are involved in DNA replication, repair, and recombination. Similarity to an E. coli protein suggests that this enzyme may be a subunit of DNA polymerase III, which does not have intrinsic exonuclease activity.

Synonyms

Three prime repair exonuclease 2;3.1.11.2;3'-5' exonuclease TREX2; TREX2

Gene Name

TREX2

Gene ID

11219

UniProt

Q9BQ50

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived human TREX2 recombinant protein (Position: E69-A279) . Human TREX2 shares 88.6% amino acid (aa) sequence identity with mouse TREX2.

Clonality

Polyclonal

Tissue Specificity

Detected in heart, breast, prostate, skeletal muscle, testis, uterus, bone marrow, colon, small intestine, stomach and thymus. .

Applications

WB

Field of Research

DNA/RNA, DNA Damage & Repair, Epigenetics and Nuclear Signaling

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Exonuclease with a preference for double-stranded DNA with mismatched 3' termini. May play a role in DNA repair. .

References & Citations

1. Entrez Gene: TREX2 three prime repair exonuclease 2. 2. Mazur DJ, Perrino FW (Aug 1999) . Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'-->5' exonucleases. J Biol Chem 274 (28) : 19655–60.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

30621 MW

Observed Molecular Weight

37 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Three prime repair exonuclease 2

Subcellular Location

Nucleus .

Protein Name

Three prime repair exonuclease 2

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

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