Anti-MPS1/RPS27 Antibody Picoband®

40S ribosomal protein S27, also known as metallopan-stimulin 1 or MPS-1, is a protein that in humans is encoded by the RPS27 gene. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S27E family of ribosomal proteins. It contains a C4-type zinc finger domain that can bind to zinc. The encoded protein has been shown to be able to bind to nucleic acid. It is located in the cytoplasm as a ribosomal component, but it has also been detected in the nucleus. Studies in rat indicate that ribosomal protein S27 is located near ribosomal protein S18 in the 40S subunit and is covalently linked to translation initiation factor eIF3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

E. coli-derived human MPS1 recombinant protein (Position: P2-H84) . Human MPS1 shares 100% amino acid (aa) sequence identity with both mouse and rat MPS1.

1. Fernandez-Pol JA (1996) . Metallopanstimulin as a novel tumor marker in sera of patients with various types of common cancers: implications for prevention and therapy. Anticancer Research 16 (4B) : 2177–85. 2. Tsui SK, Lee SM, Fung KP, Waye MM, Lee CY (Oct 1996) . Primary structures and sequence analysis of human ribosomal proteins L39 and S27. Biochemistry and Molecular Biology International 40 (3) : 611–6.

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.