Anti-FSH Receptor/FSHR Antibody Picoband®

Boster Bio Anti-FSH Receptor/FSHR Antibody Picoband® catalog # PB10065. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

The follicle-stimulating hormone receptor or FSH receptor (FSHR) is a transmembrane receptor that interacts with the follicle-stimulating hormone (FSH) and represents a G protein-coupled receptor (GPCR) . This FSHR gene is mapped to chromosome 2p21 by fluorescence in situ hybridization. The protein encoded by this gene belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants.

Synonyms

Follicle-stimulating hormone receptor; FSH-R; Follitropin receptor; FSHR; LGR1

Gene Name

FSHR

Gene ID

2492

UniProt

P23945

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived human FSH Receptor recombinant protein (Position: C18-N187) . Human FSH Receptor shares 91.2% and 90% amino acid (aa) sequence identity with mouse and rat FSH Receptor, respectively.

Clonality

Polyclonal

Tissue Specificity

Sertoli cells and ovarian granulosa cells.

Applications

Field of Research

Endocrine System, G Protein Signaling, More Gpcr, Neuroscience, Neurotransmission, Receptors / Channels, Signal Transduction, Signaling Pathway

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

References & Citations

1. Gromoll, J., Ried, T., Holtgreve-Grez, H., Nieschlag, E., Gudermann, T. Localization of the human FSH receptor to chromosome 2p21 using a genomic probe comprising exon 10. J. Molec. Endocr. 12: 265-271, 1994.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

78265 MW

Observed Molecular Weight

78 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Follicle-stimulating hormone receptor

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Name

Follicle-stimulating hormone receptor (FSH-R)

Isotype

Rabbit IgG

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

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Anti-FSH Receptor/FSHR Antibody Picoband®

Product Specifications

Background

Synonyms

Gene Name

Gene ID

UniProt

Host

Reactivity

Cross Reactivity

Immunogen

Clonality

Tissue Specificity

Applications

Field of Research

Purification

Concentration

Form

Reconstitution

Function

References & Citations

Storage Conditions

Calculated Molecular Weight

Observed Molecular Weight

Specificity

Gene Name Synonym

Subcellular Location

Protein Name

Isotype

Contents

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