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Anti-CCDC6 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Coiled-coil domain-containing protein 6 is a protein that in humans is encoded by the CCDC6 gene. This gene encodes a coiled-coil domain-containing protein. The encoded protein is ubiquitously expressed and may function as a tumor suppressor. A chromosomal rearrangement resulting in the expression of a fusion gene containing a portion of this gene and the intracellular kinase-encoding domain of the ret proto-oncogene is the cause of thyroid papillary carcinoma.

Synonyms

Coiled-coil domain-containing protein 6; Papillary thyroid carcinoma-encoded protein; Protein H4; CCDC6; D10S170, TST1

Gene Name

CCDC6

Gene ID

8030

UniProt

Q16204

Host

Rabbit

Reactivity

Human, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human CCDC6, identical to the related mouse sequence.

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed.

Applications

Flow Cytometry

Field of Research

Cell Biology, DNA/RNA, DNA Damage & Repair, DNA Damage Response, Epigenetics and Nuclear Signaling

Purification

Immunogen affinity purified.

Form

Liquid

Function

Reversible hydration of carbon dioxide.

References & Citations

1. Anne-Spence M, Falk CT, Neiswanger K, Field LL, Marazita ML, Allen FH, Siervogel RM, Roche AF, Crandall BF, Sparkes RS (Sep 1984) . Estimating the recombination frequency for the PTC-Kell linkage. Human Genetics 67 (2) : 183–6. 2. Grieco M, Cerrato A, Santoro M, Fusco A, Melillo RM, Vecchio G (Sep 1994) . Cloning and characterization of H4 (D10S170), a gene involved in RET rearrangements in vivo. Oncogene 9 (9) : 2531–5.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

53291 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Coiled-coil domain-containing protein 6

Subcellular Location

Cytoplasm. Cytoplasm, cytoskeleton . May be a cytoskeletal protein.

Protein Name

Coiled-coil domain-containing protein 6

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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