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Anti-ALDH1B1 Antibody Picoband®

Boster Bio Anti-ALDH1B1 Antibody Picoband® catalog # PB10037. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Aldehyde dehydrogenase X, mitochondrial is an enzyme that in humans is encoded by the ALDH1B1 gene. This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems.

Synonyms

Aldehyde dehydrogenase X, mitochondrial;1.2.1.3; Aldehyde dehydrogenase 5; Aldehyde dehydrogenase family 1 member B1; ALDH1B1; ALDH5, ALDHX

Gene Name

ALDH1B1

Gene ID

219

UniProt

P30837

Host

Rabbit

Reactivity

Human, Monkey, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human ALDH1B1, different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.

Clonality

Polyclonal

Tissue Specificity

Liver, testis and to a lesser extent in brain.

Applications

Flow Cytometry, IF, IHC, ICC, WB

Field of Research

Cancer, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Pathways and Processes, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation.

References & Citations

1. Dolgin E (Jun 2011) . Mouse library set to be knockout. Nature 474 (7351) : 262–3. 2. Hsu LC, Chang WC (Jul 1991) . Cloning and characterization of a new functional human aldehyde dehydrogenase gene. The Journal of Biological Chemistry266 (19) : 12257–65.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

57206 MW

Observed Molecular Weight

55 kDa

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Aldehyde dehydrogenase X, mitochondrial

Subcellular Location

Mitochondrion matrix.

Protein Name

Aldehyde dehydrogenase X, mitochondrial

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

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