Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-AEBP2 Antibody Picoband®

Boster Bio Anti-AEBP2 Antibody Picoband® catalog # PB9977. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Adipocyte Enhancer-Binding Protein is a zinc finger protein that in humans is encoded by the evolutionarily well-conserved gene AEBP2. This gene is mapped to 12p12.3. AEBP2 is a DNA-binding transcriptional repressor. It may regulate the migration and development of the neural crest cells through the PRC2-mediated epigenetic mechanism and is most likely a targeting protein for the mammalian PRC2 complex.

Synonyms

Zinc finger protein AEBP2; Adipocyte enhancer-binding protein 2; AE-binding protein 2; AEBP2

Gene Name

AEBP2

Gene ID

121536

UniProt

Q6ZN18

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human AEBP2 recombinant protein (Position: K424-Q517) . Human AEBP2 shares 98.8% amino acid (aa) sequence identity with mouse AEBP2.

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed, highest levels were found in brain and lung. Isoform 5 is expressed at higher levels in astrocytomas as compared to normal brain tissue and expression increases strikingly with the severity of the tumor, being higher in the most aggressive tumors. .

Applications

Flow Cytometry, IF, IHC, ICC, WB

Field of Research

Chromatin Binding Proteins, Chromatin Remodeling, DNA/RNA Binding, Domain Families, Epigenetics and Nuclear Signaling, Transcription, Transcription Factors, Zinc Finger

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

DNA-binding transcriptional repressor. May interact with and stimulate the activity of the PRC2 complex, which methylates 'Lys-9' and 'Lys-27' residues of histone H3. .

References & Citations

1. Imhof, Axel; Kim, Hana; Bakshi, Arundhati; Kim, Joomyeong (2015) . Retrotransposon-Derived Promoter of Mammalian Aebp2. PLOS ONE 10 (4) : e0126966. 2. Kim H, Kang K, Kim J (2009) . AEBP2 as a potential targeting protein for Polycomb Repression Complex PRC2. Nucleic Acids Res. 37 (9) : 2940–50.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

54467MW

Observed Molecular Weight

54 kDa

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Zinc finger protein AEBP2

Subcellular Location

Nucleus .

Protein Name

Zinc finger protein AEBP2

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Gzmn Mouse siRNA Oligo Duplex (Locus ID 245839)
SR406964 1 Kit

Gzmn Mouse siRNA Oligo Duplex (Locus ID 245839)

Ask
View Details
Rabbit Monoclonal Niemann-Pick type C2 Antibody (031) [Biotin]
NBP2-90211B 0.1 mL

Rabbit Monoclonal Niemann-Pick type C2 Antibody (031) [Biotin]

Ask
View Details
Cdh26 Mouse shRNA Lentiviral Particle (Locus ID 381409)
TL508603V 500 µL Each

Cdh26 Mouse shRNA Lentiviral Particle (Locus ID 381409)

Ask
View Details
TFPI Recombinant Antibody, Biotin Conjugated
bsm-62321R-Biotin 100 µL

TFPI Recombinant Antibody, Biotin Conjugated

Ask
View Details
IKs124
HY-121977-01 1 mg

IKs124

Ask
View Details
IKs124
HY-121977-02 5 mg

IKs124

Ask
View Details