Anti-VIP peptides VIP Antibody

Vasoactive intestinal peptide, also known as PHM27 or VIP, is a peptide hormone containing 28 amino acid residues. This gene is mapped to 6q25. The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.

VIP peptides; Intestinal peptide PHV-42; Peptide histidine valine 42; Intestinal peptide PHM-27; Peptide histidine methioninamide 27; Vasoactive intestinal peptide; VIP; Vasoactive intestinal polypeptide; VIP

A synthetic peptide corresponding to a sequence in the middle region of human VIP, different from the related mouse and rat sequences by four amino acids.

VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder. .

1. Fahrenkrug J, Emson PC (Sep 1982) . Vasoactive intestinal polypeptide: functional aspects. British Medical Bulletin 38 (3) : 265–70. 2. Linder S, Barkhem T, Norberg A, Persson H, Schalling M, Hökfelt T, Magnusson G (Jan 1987) . Structure and expression of the gene encoding the vasoactive intestinal peptide precursor. Proceedings of the National Academy of Sciences of the United States of America 84 (2) : 605–9. 3. Said SI (Apr 1986) . Vasoactive intestinal peptide. Journal of Endocrinological Investigation 9 (2) : 191–200.

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.