What sizes are available for Anti-ZP1 Antibody Picoband® Fluoro594 Conjugated?

Anti-ZP1 Antibody Picoband® Fluoro594 Conjugated is available in the following size(s): 100 µg/Vial.

Is Anti-ZP1 Antibody Picoband® Fluoro594 Conjugated in stock?

Anti-ZP1 Antibody Picoband® Fluoro594 Conjugated is currently made to order / not held in immediate stock. Contact us for lead time.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

Anti-ZP1 Antibody Picoband® Fluoro594 Conjugated

Q: What is the catalog number for Anti-ZP1 Antibody Picoband® Fluoro594 Conjugated?

The catalog number for Anti-ZP1 Antibody Picoband® Fluoro594 Conjugated is PB9970-Fluoro594.

Selected Variant

PB9970-Fluoro594

Size: 100 µg/Vial

Product Specifications

Background

Zona pellucida sperm-binding protein 1 (ZP1) is a protein that belopngs to the mammalian zona pellucida. The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. Zp1 ensures the structural integrity of the zona pellucida. Mutations in this gene are a cause of oocyte maturation defect and infertility. And this gene is mapped to chromosome 11q12.2.

Synonyms

Zona pellucida sperm-binding protein 1; Zona pellucida glycoprotein 1; Zp-1; Processed zona pellucida sperm-binding protein 1; ZP1

Gene Name

ZP1

Gene ID

22917

UniProt

P60852

Host

Rabbit

Reactivity

Human, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human ZP1, different from the related mouse sequence by four amino acids, and from the related rat sequence by five amino acids.

Clonality

Polyclonal

Tissue Specificity

Oocytes.

Applications

Flow Cytometry

Field of Research

Developmental Biology, Germ Cell Markers, Reproduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

The mammalian zona pellucida, which mediates species- specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP1 ensures the structural integrity of the zona pellucida.

References & Citations

1. Gross, M. B. Personal Communication. Baltimore, Md. 6/24/2014. 2. Huang, Hua-Lin; Lv, Chao; Zhao, Ying-Chun; Li, Wen; He, Xue-Mei; Li, Ping; Sha, Ai-Guo; Tian, Xiao; Papasian, Christopher J.; Deng, Hong-Wen; Lu, Guang-Xiu; Xiao, Hong-Mei (2014) . Mutant ZP1 in Familial Infertility. New England Journal of Medicine 370 (13) : 1220–1226. 3. Rankin, T., Talbot, P., Lee, E., Dean, J. Abnormal zonae pellucidae in mice lacking ZP1 result in early embryonic loss.Development 126: 3847-3855, 1999.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

70049 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

Gene Name Synonym

Zona pellucida sperm-binding protein 1

Subcellular Location

Processed zona pellucida sperm-binding protein 1: Secreted, extracellular space, extracellular matrix . The glycoproteinaceous translucent extracellular matrix that surrounds the mammalian oocyte is called zona pellucida. .

Protein Name

Zona pellucida sperm-binding protein 1

Isotype

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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