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Anti-CAP1 Antibody Picoband®

Boster Bio Anti-CAP1 Antibody Picoband® catalog # PB9923. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Adenylyl cyclase-associated protein 1 is an enzyme that in humans is encoded by the CAP1 gene. This gene is mapped to 1p34.2. The protein encoded by this gene is related to the S. cerevisiae CAP protein, which is involved in the cyclic AMP pathway. And the human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin. Alternatively spliced transcript variants have been identified.

Synonyms

Adenylyl cyclase-associated protein 1; CAP 1; CAP1; CAP

Gene Name

CAP1

Gene ID

10487

UniProt

Q01518

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E. coli-derived human CAP1 recombinant protein (Position: A2-R123) . Human CAP1 shares 92.6% and 93.4% amino acid (aa) sequence identity with mouse and rat CAP1, respectively.

Clonality

Polyclonal

Tissue Specificity

High-molecular-weight caldesmon (isoform 1) is predominantly expressed in smooth muscles, whereas low-molecular- weight caldesmon (isoforms 2, 3, 4 and 5) are widely distributed in non-muscle tissues and cells. Not expressed in skeletal muscle or heart.

Applications

WB

Field of Research

Cytoskeleton/ECM, DNA/RNA, Epigenetics and Nuclear Signaling, Extracellular Matrix, RNA Processing, Signal Transduction, Structures

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Ly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity.

References & Citations

1. Entrez Gene: CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) . 2. Hubberstey A, Yu G, Loewith R, Lakusta C, Young D (Apr 1997) . Mammalian CAP interacts with CAP, CAP2, and actin. J Cell Biochem 61 (3) : 459–66. 3. Matviw H, Yu G, Young D (Nov 1992) . Identification of a human cDNA encoding a protein that is structurally and functionally related to the yeast adenylyl cyclase-associated CAP proteins. Mol Cell Biol 12 (11) : 5033–40.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

51901 MW

Observed Molecular Weight

60 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Adenylyl cyclase-associated protein 1

Subcellular Location

Cell membrane ; Peripheral membrane protein .

Protein Name

Adenylyl cyclase-associated protein 1

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

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