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Anti-Prolactin Prl Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Prolactin (PRL) also known as luteotropic hormone (LTH) is a protein that in humans is encoded by the PRL gene. Prolactin is a peptide hormone discovered by Henry Friesen. Although it is perhaps best known for its role in lactation, prolactin already existed in the oldest known vertebrates-fishes-where its most important functions were probably related to control of water and salt balance. Prolactin also acts in a cytokine-like manner and as an important regulator of the immune system. Prolactin has important cell cycle related functions as a growth-, differentiating- and anti-apoptotic factor. As a growth factor binding to cytokine like receptors it has also profound influence on hematopoiesis, angiogenesis and is involved in the regulation of blood clotting through several pathways.

Synonyms

Prolactin; PRL; Prl

Gene Name

Prl

Gene ID

19109

UniProt

P06879

Host

Rabbit

Reactivity

Mouse

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E. coli-derived mouse Prolactin recombinant protein (Position: L30-C226) .

Clonality

Polyclonal

Tissue Specificity

Restricted to a subset of activated T-cells. .

Applications

Flow Cytometry

Field of Research

Growth Factors/Hormones, Lipid Metabolism, Metabolism, Protein Phosphorylation, Receptor Tyrosine Kinases, Signal Transduction, Tyrosine Kinases

Purification

Immunogen affinity purified.

Form

Liquid

Function

Prolactin acts primarily on the mammary gland by promoting lactation.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

25496 MW

Applications Notes

6

Gene Name Synonym

Prolactin

Subcellular Location

Secreted.

Sequence Similarities

Belongs to the MIF family.

Protein Name

Prolactin (PRL)

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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