Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-FMO2 Antibody Picoband®

Boster Bio Anti-FMO2 Antibody Picoband® catalog # PB9760. Tested in WB applications. This antibody reacts with Human; Mouse; Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Dimethylaniline monooxygenase [N-oxide-forming] 2 is an enzyme that in humans is encoded by the FMO2 gene. This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants.

Synonyms

Dimethylaniline monooxygenase [N-oxide-forming] 2;1.14.13.8; Dimethylaniline oxidase 2; FMO 1B1; Pulmonary flavin-containing monooxygenase 2; FMO 2; FMO2

Gene Name

FMO2

Gene ID

2327

UniProt

Q99518

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human FMO2, different from the related mouse and rat sequences by two amino acids.

Clonality

Polyclonal

Tissue Specificity

Expressed in lung (at protein level) . Expressed predominantly in lung, and at a much lesser extent in kidney. Also expressed in fetal lung, but not in liver, kidney and brain. .

Applications

WB

Field of Research

Cancer, Drug Metabolism, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Catalyzes the N-oxidation of certain primary alkylamines to their oximes via an N-hydroxylamine intermediate. Inactive toward certain tertiary amines, such as imipramine or chloropromazine. Can catalyze the S-oxidation of methimazole. The truncated form is catalytically inactive. .

References & Citations

1. Entrez Gene: FMO2 flavin containing monooxygenase 2 (non-functional) . 2. Dolphin CT, Shephard EA, Povey S, Smith RL, Phillips IR (Nov 1992) . Cloning, primary sequence and chromosomal localization of human FMO2, a new member of the flavin-containing mono-oxygenase family.Biochem J. 287. (Pt 1) : 261–7. 3. Dolphin CT, Beckett DJ, Janmohamed A, Cullingford TE, Smith RL, Shephard EA, Phillips IR (Dec 1998) . The flavin-containing monooxygenase 2 gene (FMO2) of humans, but not of other primates, encodes a truncated, nonfunctional protein. J Biol Chem 273 (46) : 30599–607.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

61 kDa

Observed Molecular Weight

61 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Dimethylaniline monooxygenase [N-oxide-forming] 2

Subcellular Location

Microsome membrane. Endoplasmic reticulum membrane.

Protein Name

Dimethylaniline monooxygenase [N-oxide-forming] 2

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Myocos Mouse Gene Knockout Kit (CRISPR)
KN500495 1 Kit

Myocos Mouse Gene Knockout Kit (CRISPR)

Ask
View Details
SEC61A2 (NM_001142627) Human Tagged ORF Clone Lentiviral Particle
RC227606L4V 200 µL

SEC61A2 (NM_001142627) Human Tagged ORF Clone Lentiviral Particle

Ask
View Details
SEL1L2 Protein Lysate (Human) with C-Ha Tag
43326031 100 µg

SEL1L2 Protein Lysate (Human) with C-Ha Tag

Ask
View Details
Bcl 2 Human (minus BH1 domain)
OM303582-01 2 µg

Bcl 2 Human (minus BH1 domain)

Ask
View Details
Bcl 2 Human (minus BH1 domain)
OM303582-02 10 µg

Bcl 2 Human (minus BH1 domain)

Ask
View Details
Bcl 2 Human (minus BH1 domain)
OM303582-03 1 mg

Bcl 2 Human (minus BH1 domain)

Ask
View Details