Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Prealbumin/TTR Antibody Picoband®

Boster Bio Anti-Prealbumin/TTR Antibody Picoband® catalog # PB9749. Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Transthyretin (TTR) is also known as prealbumin. It is mapped to chromosome region 18q11.2-q12.1. This gene encodes a carrier protein responsible for the transport of thyroid hormones and retinol. The protein consists of a tetramer of identical subunits. Due to increased stability of the tetramer form of this encoded protein in mouse, compared to the human protein, this gene product has a reduced tendency to form amyloid fibrils. In humans, this protein binds beta-amyloid preventing its aggregation and providing a neuroprotective role in Alzheimer's disease.

Synonyms

Transthyretin; ATTR; Prealbumin; TBPA; TTR; PALB

Gene Name

TTR

Gene ID

7276

UniProt

P02766

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Prealbumin recombinant protein (Position: G21-E147) . Human Prealbumin shares 81% and 83.3% amino acid (aa) sequence identity with mouse and rat Prealbumin, respectively.

Clonality

Polyclonal

Tissue Specificity

Detected in serum and cerebrospinal fluid (at protein level) . Highly expressed in choroid plexus epithelial cells. Detected in retina pigment epithelium and liver. .

Applications

ELISA (Cap), IHC, WB

Field of Research

Alzheimer's Disease, Cardiovascular, Neurodegenerative Disease, Neurology Process, Neuroscience, Serum Proteins

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. .

References & Citations

1. Benson, M. D., Dwulet, F. E. Identification of carriers of a variant plasma prealbumin (transthyretin) associated with familial amyloidotic polyneuropathy type I. J. Clin. Invest. 75: 71-75, 1985. 2. Sparkes, R. S., Sasaki, H., Mohandas, T., Yoshioka, K., Klisak, I., Sakaki, Y., Heinzmann, C., Simon, M. I. Assignment of the prealbumin (PALB) gene (familial amyloidotic polyneuropathy) to human chromosome region 18q11.2-q12.1. Hum. Genet. 75: 151-154, 1987.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

15887 MW

Observed Molecular Weight

14 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Transthyretin

Subcellular Location

Secreted. Cytoplasm.

Protein Name

Transthyretin

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

More Discoveries

Explore Other Products

Browse additional items from our catalog

Kcnip2 (NM_145703) Mouse Recombinant Protein
PM43179M5 20 µg

Kcnip2 (NM_145703) Mouse Recombinant Protein

Sign In for Pricing
View Details
Recombinant Monoclonal Anti- MSH6 antibody
BRM1077-2 100 µL

Recombinant Monoclonal Anti- MSH6 antibody

Sign In for Pricing
View Details
Fatty Acid Synthase (FASN) Human ELISA Kit
95713 96 Tests

Fatty Acid Synthase (FASN) Human ELISA Kit

Sign In for Pricing
View Details
Ascc1 (NM_001007632) Rat Tagged Lenti ORF Clone
RR206154L4 10 µg

Ascc1 (NM_001007632) Rat Tagged Lenti ORF Clone

Sign In for Pricing
View Details
Recombinant Human CXCL11/I-TAC Protein, N-GST
E55P0216 50 µg

Recombinant Human CXCL11/I-TAC Protein, N-GST

Sign In for Pricing
View Details
Mouse KLHDC8B shRNA Plasmid
abx978880-01 150 µg

Mouse KLHDC8B shRNA Plasmid

Sign In for Pricing
View Details