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Anti-Oligodendrocyte myelin glycoprotein/OMG Antibody Picoband®

Boster Bio Anti-Oligodendrocyte myelin glycoprotein/OMG Antibody Picoband® catalog # PB9730. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Oligodendrocyte-myelin glycoprotein is a protein that in humans is encoded by the OMG gene. This gene is mapped to 17q11-q12. OMG, like neurofibromin (NF1), has growth suppressive effects and downregulates mitogenic signaling pathways closely related to those influenced by neurofibromin. Overexpression of OMG alters mitogenic signaling in fibroblasts. Cells overexpressing OMG grow more slowly in serum compared to controls and show a partial G1 block upon cell cycle analysis.

Synonyms

Oligodendrocyte-myelin glycoprotein; OMG; OMGP

Gene Name

OMG

Gene ID

4974

UniProt

P23515

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human OMG, different from the related mouse sequence by two amino acids.

Clonality

Polyclonal

Tissue Specificity

Oligodendrocytes and myelin of the central nervous system.

Applications

WB

Field of Research

Cell Adhesion Proteins, Cell Type Marker, Membrane Proteins, Neuroscience

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system.

References & Citations

1. Entrez Gene: OMG oligodendrocyte myelin glycoprotein. 2. Mikol DD, Alexakos MJ, Bayley CA, Lemons RS, Le Beau MM, Stefansson K (Mar 1991) . Structure and chromosomal localization of the gene for the oligodendrocyte-myelin glycoprotein. J Cell Biol 111 (6 Pt 1) : 2673–9. 3. Viskochil D, Cawthon R, O'Connell P, Xu GF, Stevens J, Culver M, Carey J, White R (Mar 1991) . The gene encoding the oligodendrocyte-myelin glycoprotein is embedded within the neurofibromatosis type 1 gene. Mol Cell Biol 11 (2) : 906–12.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

49608 MW

Observed Molecular Weight

50 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Oligodendrocyte-myelin glycoprotein

Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor.

Protein Name

Oligodendrocyte-myelin glycoprotein

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

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