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Anti-MIG/CXCL9 Antibody Picoband®

Boster Bio Anti-MIG/CXCL9 Antibody Picoband® catalog # PB9694. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

MIG, also known as CXCL9, is a T-cell chemoattractant inducible by gamma interferon that is a member of the CXC chemokine family of cytokines.?This gene is mapped to 4q21. It is noted that, although the best-described activities of the chemokines are as chemotactic factors, chemokines also have an effect on T-cell activation, angiogenesis, and HIV infection. While most CXC chemokines are chemotactic for neutrophils, MIG and INP10 are unusual and similar in being CXC chemokines that are chemotactic for lymphocytes and inactive in neutrophils.

Synonyms

C-X-C motif chemokine 9; Gamma-interferon-induced monokine; Monokine induced by interferon-gamma; HuMIG; MIG; Small-inducible cytokine B9; CXCL9; CMK, MIG, SCYB9

Gene Name

CXCL9

Gene ID

4283

UniProt

Q07325

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E. coli-derived human CXCL9 recombinant protein (Position: T23-T125) . Human CXCL9 shares 68.2% amino acid (aa) sequence identity with mouse CXCL9.

Clonality

Polyclonal

Applications

ELISA, WB

Field of Research

Chemokines, Immunology, Innate Immunity

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3.

References & Citations

1. Lee HH, Farber JM (1996) . Localization of the gene for the human MIG cytokine on chromosome 4q21 adjacent to INP10 reveals a chemokine mini-cluster. Cytogenet. Cell Genet. 74 (4) : 255–8. 2. O'Donovan N, Galvin M, Morgan JG (1999) . Physical mapping of the CXC chemokine locus on human chromosome 4. Cytogenet. Cell Genet. 84 (1-2) : 39–42. 3. Tensen CP, Flier J, Van Der Raaij-Helmer EM, Sampat-Sardjoepersad S, Van Der Schors RC, Leurs R, Scheper RJ, Boorsma DM, Willemze R (1999) . Human IP-9: A keratinocyte-derived high affinity CXC-chemokine ligand for the IP-10/Mig receptor (CXCR3) . J. Invest. Dermatol. 112 (5) : 716–22.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

14019 MW

Observed Molecular Weight

19 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

C-X-C motif chemokine 9

Subcellular Location

Secreted.

Protein Name

C-X-C motif chemokine 9

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

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