Anti-Lymphotactin/XCL1 Antibody Picoband® Fluoro647 Conjugated

Chemokine (C motif) ligand (XCL1) is a small cytokine belonging to the XC chemokine family that is also known as lymphotactin. Muller et al. (1995) mapped the gene to chromosome 1q23 by FISH. The sequence of the deduced 114-amino acid protein is most homologous to the CC chemokines CCL8 and CCL3. It is found in high levels in spleen, thymus, intestine and peripheral blood leukocytes, and at lower levels in lung, prostate gland and ovary. XCL1 induces the migration of cells expressing XCR1.

Lymphotactin; ATAC; C motif chemokine 1; Cytokine SCM-1; Lymphotaxin; SCM-1-alpha; Small-inducible cytokine C1; XC chemokine ligand 1; XCL1; LTN, SCYC1

E.coli-derived human Lymphotactin recombinant protein (Position: V22-G114) . Human Lymphotactin shares 60.2% and 57% amino acid (aa) sequence identity with mouse and rat Lymphotactin, respectively.

1. Kennedy J, Kelner G, Kleyensteuber S, Schall T, Weiss M, Yssel H, Schneider P, Cocks B, Bacon K, Zlotnik A (1995) . Molecular cloning and functional characterization of human lymphotactin. J Immunol 155 (1) : 203–9. PMID 7602097. 2. Kennedy, J., Kelner, G. S., Kleyensteuber, S., Schall, T. J., Weiss, M. C., Yssel, H., Schneider, P. V., Cocks, B. G., Bacon, K. B., Zlotnik, A.Molecular cloning and functional characterization of human lymphotactin.J. Immun.155: 203-209, 1995. 3. Yoshida T, Imai T, Kakizaki M, Nishimura M, Takagi S, Yoshie O (1998) . Identification of single C motif-1/lymphotactin receptor XCR1. J Biol Chem 273 (26) : 16551–4.