Anti-Lysozyme/LYZ Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
In humans, the lysozyme enzyme is encoded by the LYZ gene. This gene encodes human lysozyme, whose natural substrate is the bacterial cell wall peptidoglycan (cleaving the beta [1-4] glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine) . Lysozyme is one of the antimicrobial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. The protein has antibacterial activity against a number of bacterial species. Missense mutations in this gene have been identified in heritable renal amyloidosis.
Synonyms
Lysozyme C;3.2.1.17;1,4-beta-N-acetylmuramidase C; LYZ; LZM
Gene Name
LYZ
Gene ID
4069
UniProt
P61626
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Lysozyme.
Clonality
Polyclonal
Tissue Specificity
Cornea and other tissues.
Applications
Flow Cytometry
Field of Research
Cell Biology, Immunology, Innate Immunity, Macrophage/Inflammation, Organelles, Subcellular Markers, Tags & Cell Markers
Purification
Immunogen affinity purified.
Form
Liquid
Function
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte- macrophage system and enhance the activity of immunoagents.
References & Citations
1. McKenzie HA, White FH (1991) . Lysozyme and alpha-lactalbumin: structure, function, and interrelationships. Adv. Protein Chem. 41: 173–315. 2. Peters CW, Kruse U, Pollwein R, Grzeschik KH, Sippel AE (July 1989) . The human lysozyme gene. Sequence organization and chromosomal localization. Eur. J. Biochem. 182 (3) : 507–16. 3. Yoshimura K, Toibana A, Nakahama K (January 1988) . Human lysozyme: sequencing of a cDNA, and expression and secretion by Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun. 150 (2) : 794–801.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
16537 MW
Specificity
No cross reactivity with other proteins.
Applications Notes
6
Gene Name Synonym
Lysozyme C
Subcellular Location
Secreted.
Protein Name
Lysozyme C
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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