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Anti-Protein Wnt-7a Wnt7a Antibody Picoband®

Boster Bio Anti-Protein Wnt-7a Wnt7a Antibody catalog # RP1088. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi / Raas – Rothschild / Schinzel phocomelia syndromes.

Synonyms

Protein Wnt-7a; WNT7A

Gene Name

WNT7A

Gene ID

7476

UniProt

O00755

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Wnt7a, identical to the related mouse sequence.

Clonality

Polyclonal

Tissue Specificity

Expression is restricted to placenta, kidney, testis, uterus, fetal lung, and fetal and adult brain.

Applications

Flow Cytometry, WB

Field of Research

Stem Cells

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. Signaling by Wnt-7a allows sexually dimorphic development of the mullerian ducts (By similarity) . .

References & Citations

1. Dang Y, Qin Y, Tang R, Mu Y, Li G, Xia M, Chen ZJ. “Variants of the WNT7A gene in Chinese patients with müllerian duct abnormalities.” Fertil Steril, 2012 Feb. 2. Kondratov AG, Kvasha SM, Stoliar LA, Romanenko AM, Zgonnyk YM, Gordiyuk VV, Kashuba EV, Rynditch AV, Zabarovsky ER, Kashuba VI. “Alterations of the WNT7A gene in clear cell renal cell carcinomas.” PLoS One, 2012.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

39005 MW

Observed Molecular Weight

39 kDa

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Protein Wnt-7a

Subcellular Location

Secreted, extracellular space, extracellular matrix.

Sequence Similarities

Belongs to the Mediator complex subunit 25 family. PTOV1 subfamily.

Protein Name

Protein Wnt-7a

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

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