Anti-Cystatin A/CSTA Antibody Picoband® Fluoro647 Conjugated

Cystatin A also called Stefin A is a protein that in humans is encoded by the CSTA gene. Cystatin A is a cysteine proteinase inhibitor that belongs to family 1 of the cystatin superpamily. This gene was assigned to human chromosome 3q21.1. This is an intracellular thiol proteinase inhibitor. Cystatin A plays an important role in desmosome-mediated cell-cell adhesion in the lower levels of the epidermis. Stefins have been proposed as prognostic and diagnostic tools for cancer.

E.coli-derived human Cystatin A recombinant protein (Position: E8-F98) . Human Cystatin A shares 61.5% and 58.2% amino acid (aa) sequence identity with mouse and rat Cystatin A, respectively.

Apoptosis, Cancer, Caspases, Cell Biology, Cytoskeleton/ECM, ECM Enzymes, Extracellular Matrix, Intracellular, Invasion/Microenvironment, Signal Transduction

This is an intracellular thiol proteinase inhibitor. Has an important role in desmosome-mediated cell-cell adhesion in the lower levels of the epidermis. .

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