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Anti-Carbonic Anhydrase I/CA1 Antibody Picoband®

Boster Bio Anti-Carbonic Anhydrase I/CA1 Antibody Picoband® catalog # PB9529. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Carbonic anhydrase 1 is an enzyme that in humans is encoded by the CA1 gene. It is a member of the Carbonic anhydrase. The CA1 gene is mapped to 8q22. CAI has got about 260 amino acids. This protein is highly expressed in erythrocytes. As catalysts of the reversible hydration of carbon dioxide, CAI participates in a variety of biologic processes like respiration, calcification, acid-base balance etc.

Synonyms

Carbonic anhydrase 1;4.2.1.1; Carbonate dehydratase I; Carbonic anhydrase B; CAB; Carbonic anhydrase I; CA-I; CA1

Gene Name

CA1

Gene ID

759

UniProt

P00915

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human CA1 recombinant protein (Position: D9-F261) . Human CA1 shares 78.5% and 81% amino acid (aa) sequence identity with mouse and rat CA1, respectively.

Clonality

Polyclonal

Tissue Specificity

Highly expressed in fetal lung, and kidney. In the adult, expression is mainly seen in lymphoid tissues, including spleen, thymus and peripheral blood lymphocytes.

Applications

Flow Cytometry, IF, IHC, ICC, WB

Field of Research

Angiogenesis, Cancer, Cell Adhesion, Cell Adhesion Proteins, Cytoskeleton/ECM, ECM Enzymes, Extracellular Matrix, Invasion/Microenvironment, Membrane Proteins, Neuroscience, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea. .

References & Citations

1. Lowe N, Edwards YH, Edwards M, Butterworth PH (Nov 1991) . Physical mapping of the human carbonic anhydrase gene cluster on chromosome 8. Genomics 10 (4) : 882–8. 2. Entrez Gene: CA1 carbonic anhydrase I.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

28870 MW

Observed Molecular Weight

29 kDa

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Carbonic anhydrase 1

Subcellular Location

Cytoplasm.

Sequence Similarities

Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

Protein Name

Carbonic anhydrase 1

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

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